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Published on Oct 20, 2014
This talk was given at a local TEDx event, produced independently of the TED Conferences. Dr. Braun is currently reconstructing the genealogy of the connexin 26 gene, which causes much of the congenital deafness in the American deaf community. The overall goal of this project is to answer some fundamental questions about why and how the large number of current connexin 26 mutations first appeared, and what these mutations and their histories can tell us about human evolution. There is some fascinating evidence that connexin 26 mutations might make deaf individuals resistant to diarrheal diseases such as dysentery and cholera, a major cause of death over the past 2,000 years.
Derek Braun is a professor and geneticist at Gallaudet University’s Department of Science, Technology and Mathematics. Gallaudet is the world’s only liberal arts university for deaf and hard-of-hearing students. He oversees the Molecular Genetics Laboratory, where deaf undergraduate students perform research alongside deaf faculty. Research interests include mutations in the connexin 26 gene, which are responsible for up to half of congenital deafness in many world populations.
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