Gabriel Filippi

In 1998, at the age of 20, I took Zyprexa for just 1 month. Within weeks, I experienced rapid and severe weight gain that led to type 2 diabetes. More devastatingly, I noticed a profound change in my neurological function—a complete loss of response to psychoactive substances that had previously been a significant part of my life.
Substances that once produced powerful effects—LSD, cannabis, Salvia divinorum, and others—suddenly had no impact on me whatsoever. This wasn't a matter of tolerance; it was a complete and permanent shutdown of my brain's receptor systems.
For years, I struggled to understand what had happened to me. Medical professionals dismissed my concerns, attributing my symptoms to my underlying condition rather than the medication itself. It wasn't until I connected with other survivors and began researching the scientific literature that I realized I wasn't alone—and that what I had experienced had a name: a "chemical lobotomy."