PALSONIFY™ (paltusotine)

PALSONIFY™ (paltusotine) is a prescription medicine used to treat adults with acromegaly for whom surgery was not effective or surgery is not an option. It is not known if PALSONIFY is safe and effective in children.

This content is intended for adult US audiences only. Please see the links below for Important Safety Information and Full Prescribing Information.

The most common side effects of PALSONIFY include diarrhea, pain in your stomach (abdominal) area, nausea and vomiting, decreased appetite, slow heart rate (bradycardia), high blood sugar levels (hyperglycemia), and irregular heartbeat (palpitations).

These are not all the possible side effects of PALSONIFY. 
For more information, ask your healthcare provider or pharmacist.

©2026 Crinetics Pharmaceuticals, Inc. PALSONIFY is a trademark of Crinetics Pharmaceuticals, Inc. All rights reserved. US-PAL-2500230-01 01/26