Cure MLD

We are a global network of patient advocates and nonprofits dedicated to helping families impacted by metachromatic leukodystrophy (MLD). We are here to connect you with resources, information, support, and others dealing with MLD.   Support for this site comes from Chloe’s Fight, Love for Loie, Gavin Flying for a Cure, the Calliope Joy Foundation, and other MLD families around the world.

Metachromatic leukodystrophy (MLD) is a recessive, genetic disorder. The incidence of MLD may range from 1 in 40,000 to 1 in 100,000,  which means around 3,600 babies are born with the disorder each year. About 1 in 100 people are carriers of the ARSA mutation MLD. Two MLD carrier parents can have healthy children but there is also 25 percent chance they will have a child impacted by MLD.