Brighter Hope Foundation

Brighter Hope Foundation is a nonprofit organization whose mission is to connect families affected by Generalized Arterial Calcification of Infancy (GACI) or Hypophosphatemic Rickets caused by ENPP1 or ABCC6 Deficiencies to each other and to the medical community. The organization strives to provide current educational resources and supports ongoing research. Brighter Hope Foundation is…circulating hope.

GACI is a rare genetic disease that primarily affects the circulatory system.  GACI causes an abnormal buildup of calcium within the walls of the arteries.  This can cause critical blockages which can reduce blood flow to organs which in turn can cause stroke, heart attack, and death.

Patients with ARHR2 suffer from low phosphate levels in the blood as a result of renal phosphate wasting. The correct balance of phosphate is essential for the normal formation of bones and teeth. Symptoms can include bone pain, bone deformity, short stature, fatigue, and dental issues.