Case It molecular biology simulations

The Case It project provides a framework for collaborative case-based learning via free molecular biology simulation software (Case It v705).  The simulation enables users to perform laboratory procedures on any DNA or protein sequence, including qPCR, SNP and expression microarrays, restriction enzyme digestion, gel electrophoresis, PCR, ELISA, Southern and Western blots, and dot blots.  Students can also use the simulation to replicate Nobel Prize-winning CRISPR and mRNA experiments.  Case It v705 runs on both Windows and the Mac OS and is available at the Case It web site (link below).

Case It won a Science Prize from the American Association of Science (AAAS) for its effectiveness in undergraduate biology and high school education.  An essay describing the project was published in Science magazine (link below ).  Case It software was developed with funding from the National Science Foundation, which also supported extensive classroom testing and evaluation of project materials.