Monobenzone cream

Depigmentation is typically done with a topical cream called monobenzone. Monobenzone works by destroying the melanocytes, which are the cells that produce melanin. Melanin is the pigment that gives skin its color.

Monobenzone is applied to the unaffected areas of skin twice a day. It usually takes several weeks or months for the skin to lighten. Once the skin has lightened, it is important to avoid sun exposure, as this can darken the skin again.

Depigmentation is a permanent treatment. It is important to use sunscreen with an SPF of 30 or higher every day, even on cloudy days. People who have depigmentation should avoid tanning beds and sunlamps.

Depigmentation can be a good option for people who have tried other treatments for vitiligo without success.