Rethink Bronchiectasis

This is a channel for healthcare professionals managing and treating bronchiectasis. 

Bronchiectasis has been characterized in scientific literature as a vicious vortex consisting of 4 primary drivers, with management of the disease focused on 3: impaired mucociliary clearance, chronic airway infection, and lung destruction. The fourth driver, chronic airway inflammation, is primarily driven by an overactivity of neutrophils. Neutrophils normally help protect the lungs from harm, but in bronchiectasis they can contribute to chronic inflammation. This can contribute to lung destruction and an increased risk of future exacerbations. 

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NP-BE-US-00743