Lost my Vanquisher character Alita to Hard / Hardcore mode in Torchlight, where death is permanent. Here's a little tribute video made of fraps footage taken while playing the last few minutes of her life, taken just for test purposes.
A painful loss, as she had an epic 2-handed rifle with Fastest Attack Speed doing 478 dps, and some great equipment... Ah well, that's life, isn't it? (less info)