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  1. 1

    World's Leaders Drive Precision Medicine Forward at OME Summit

    by UCSFPublicAffairs 519 views

    The world's foremost thinkers, creators and innovators convene at the OME Summit at UC San Francisco to make precision medicine a reality. Hailing from diverse backgrounds -- from government leaders to physicians and tech entrepreneurs -- they come together to identify and take action on new approaches and projects that could harness the wealth of information from genetics and health records to transform medicine worldwide.

    To join the movement: www.MeForYou.org
    To learn more about OME 2013: http://bit.ly/11aDiqH

  2. 2

    Embryonic Stem Cells Generate Immune System

    by UCSFPublicAffairs 421 views

    Researchers at UC San Francisco have developed thymus tissue from human embryonic cells and used it to generate an immune system in mice. The achievement has the potential to lead to therapies to prevent organ transplant rejection, and to treat autoimmune diseases and immunodeficiency diseases.

    Read more: http://www.ucsf.edu/news/2013/05/106006/stem-cell-based-stra­tegy-boosts-immune-system-mice

  3. 3

    UCSF and Precision Medicine

    by UCSFPublicAffairs 585 views

    Jeffrey Bluestone, PhD, executive vice chancellor and provost, talks about how UC San Francisco is driving the field of precision medicine. This field promises to harness the vast advances in technology, genetics and biomedical research to understand the roots of disease, develop targeted therapies, and ultimately provide personal, predictive and preventive care to patients worldwide. "Today, we diagnose diabetes based on signs and symptoms, such as high blood sugar, and we treat people with the medication that works for some, but not all, patients. The promise of precision medicine is that one day we would be able to exactly identify the molecular basis of diseases such as diabetes in each individual and then identify the best therapy with the fewest side effects for an individual patient. For anyone who has lived with diabetes, that is an exciting concept."

  4. 4

    Obesity and America's Hidden Hunger Epidemic by Dr. Hilary Seligman, MD, MAS

    by UCSFPublicAffairs 92 views

    http://sfgh.ucsf.edu/research

    Dean's Seminar 2/1/13, "Obesity and America's Hidden Hunger Epidemic" by Dr. Hilary Seligman, MD, MAS - Assistant Professor of Medicine and of Epidemiology and Biostatistics Division of General Internal Medicine, UCSF Center for Vulnerable Populations at San Francisco General Hospital

  5. 5

    Depth of Field: Service Learning at UCSF

    by UCSFPublicAffairs 500 views

    All four UCSF schools and its Graduate Division offer outreach efforts in community health that help patch holes in San Francisco's safety net. As important as the services delivered, perhaps, is their fulfillment of the students' strong need to give back.

  6. 6

    UCSF Prepares Ambitious Reboot of Medical School Curriculum

    by UCSFPublicAffairs 917 views

    http://meded.ucsf.edu/bridges

    The US health care system costs over $2.5 trillion per year and still we rank 16th behind other wealthy nations in overall health. Medical schools have long claimed to train future leaders who will fix this broken system, yet things are slow to improve. This is because we fail to provide them with the skills to understand complex health care systems, navigate vast data networks, and work in truly collaborative teams.

    The goal of the UCSF Bridges Curriculum is to better prepare physicians to contribute more than clinical expertise to the complex systems in which they work. Students, and the physicians they will become, need to collaboratively and continuously innovate to improve our health care and biomedical discovery systems.

    To do this, Bridges will provide authentic workplace learning experiences that leverage the talents and commitment of our students to improve health today while sustaining these skills in future practice.

  7. 7

    "Nanobodies" Shed Light on Largest Pharmaceutical Class

    by UCSFPublicAffairs 111 views

    The largest class of pharmaceuticals target protein molecules on cell surfaces. But as shown in this movie, UC San Francisco scientists using tiny "nanobodies" now have discovered that these targeted proteins remain active inside the cell, possibly a key to better understanding drugs' effectiveness and side effects. The proteins are called G-protein coupled receptors (GPCRs), the focus of Nobel-Prize-winning research in 2012.

  8. 8

    Gerri Willis Interviews Dr. Jeffrey Olgin on FOX Business News

    by UCSFPublicAffairs 225 views

    UCSF Division of Cardiology Chief Dr. Jeffrey Olgin appeared live on FOX Business News' "The Willis Report" to talk to Gerri Willis about the Health eHeart Study, an ambitious cardiovascular study that can help physicians better understand how the heart functions and to develop new ways to predict and prevent cardiovascular disease. The goal is to enroll 1 million people from all over the world. To find out more about the study or to enroll, go here: https://www.health-eheartstudy.org. To read more about why this study is revolutionary, go here: http://www.ucsf.edu/news/2013/03/13695/study-uses-mobile-tec­hnology-help-predict-and-prevent-heart-disease.

  9. 9

    UCSF: Leading Revolutions in Health

    by UCSFPublicAffairs 472 views

    UC San Francisco is leading revolutions in health through cutting-edge biomedical research, outstanding patient care and training the health care leaders of tomorrow. As the nation's preeminent university singularly focused on health, UCSF is home to five Nobel laureates, as well as thousands of scientists and clinicians who are working to solve health's biggest mysteries. UCSF Shaw Prize recipients discuss the research they and others are conducting on campus and their hopes for using that research to benefit humanity. UCSF is convening the world's brightest and most innovative minds to spur the next revolution in health: precision medicine, which aims to provide precise, predictive and transformative care to every patient, worldwide. This UCSF video includes Chinese subtitles.

  10. 11

    Online Cardiovascular Study to Help Predict and Prevent Heart Disease

    by UCSFPublicAffairs 942 views

    http://www.ucsf.edu/news/2013/03/13695/study-uses-mobile-tec­hnology-help-predict-and-prevent-heart-disease

    A UC San Francisco team has developed an ambitious online cardiovascular study using mobile smartphones, with the goal of enrolling one million people from all over the world to improve heart health.

    Through the "Health eHeart Study," which launched Tuesday, physicians hope to better understand how the heart functions and to develop new ways to predict and prevent cardiovascular disease by harnessing the power of online and mobile smartphone technology. The study is funded by Salesforce.com Foundation.

    "We hope to be able to collect copious amounts of data on a large segment of the population so we can develop robust and accurate models to predict the occurrence of heart disease in people who don't yet have it, or slow the progression in people who already have heart disease," said cardiac electrophysiologist Jeffrey Olgin, MD, chief of the UCSF Division of Cardiology.

    UCSF researchers are working with mobile app developers to collect the information by allowing participants to submit data via a secure online survey. The study uses smartphone technology to measure a participant's heart rate, blood pressure and pulse rate. This information is sent back to researchers, who can make recommendations to help prevent or treat heart disease.

    A major goal of the Health eHeart Study is to make health care delivery more precise. The concept of Precision Medicine, which emerged from a 2010 National Academy of Sciences report co-authored by UCSF Chancellor Susan Desmond-Hellmann, MD, MPH, and Charles Sawyers, MD, of Memorial Sloan-Kettering Cancer Center, is to transform medical care worldwide by integrating the wealth of data emerging from both the human genome and research on the molecular basis of disease, with information from patients' health records and environmental data. Precision medicine has become a driving vision for UCSF, the nation's largest and most renowned university focused exclusively on health sciences.

    "With this platform, we hope to be able to diagnose and treat heart patients more rapidly than is currently done with traditional research, since we'll have a large patient population," Olgin said. "And because these patients are connected to us electronically and through their smartphones, we can deploy the study very quickly."

    The apps and certain study-related devices are free to participants. Olgin and his team plan to analyze the data to identify patterns. This will allow them to not only identify "population-based" predictors, but also to identify deviations from baselines. Participants will not receive direct feedback about their health from the study.

    Interested individuals who want to be a part of UCSF's Health eHeart Study can learn more and sign up here: https://www.health-eheartstudy.org/

    Video shot, edited and produced by Leland Kim.

  11. 12

    The Sepsis Bus: An Innovative approach to Patient Safety at UCSF

    by UCSFPublicAffairs 657 views

    Last Fall, as part of a Bay Area initiative to reduce sepsis, a large bus was stationed outside of UCSF Medical Center. Inside was a mannequin that talks, breathes, moans and turns blue - all to provide UCSF clinicians with a realistic experience to improve their ability to identify and treat sepsis patients as early as possible.

    In this video, Joshua Adler, MD, the Chief Medical Officer of UCSF MEdical Center, describes how every minute can make a difference in whether a patient with sepsis survives.

    Septicemia, or sepsis, is a serious bloodstream infection that rapidly can become life threatening and require urgent and comprehensive care. The incidence is climbing as people live longer. According to the Centers for Disease Control and Prevention, the hospitalization rate of people with a principal diagnosis of sepsis more than doubled from 2000 through 2008, increasing from 11.6 to 24 per 10,000 people. Reasons for the increases may include an aging population with more chronic illnesses; greater use of invasive procedures, the use of immunosuppressive drugs, chemotherapy, organ transplantation; and increasing microbial resistance to antibiotics.

    For hospitals like UCSF Medical Center, sepsis is especially important because the hospital treats a large number of highly complex patients with cancer, organ transplants, and others who have a weakened immune system.

    As Dr. Adler explains, UCSF has had a dramatic reduction in patient deaths from sepsis over the last ten years. From 2003 to 2011, UCSF has seen a 36 percent reduction in its sepsis mortality. The gains are the result of concentrated efforts including improved ventilator management, increased antibiotic use, keeping patients' blood pressure steady, and reducing possible complications, such as gastrointestinal bleeding and skin injuries that can result from staying in an intensive care unit.

    Sepsis Bus Video by Jason Bardi, Karin Rush-Monroe
    @jasonbardi
    jason.bardi@ucsf.edu

    For more information, see: http://www.ucsf.edu

  12. 13

    New Clinical Tool Assesses Health Risks for Older Adults

    by UCSFPublicAffairs 650 views

    http://www.ucsf.edu/news/2013/03/13614/new-clinical-tool-ass­esses-health-risks-older-adults

    A UC San Francisco team has developed a tool that can help determine -- and perhaps influence -- senior citizens' 10-year survivability rates.

    The simple checklist helps doctors assess health risks that influence the longevity of older adults, and according to the authors, could be an opportunity for seniors to really engage with their primary care provider in having informed discussions about their health care maintenance.

    The UCSF team created a 12-item "mortality index" based on data of more than 20,000 adults over the age of 50 from 1998 until 2008, from the Health and Retirement Study (HRS), a nationally-representative sample of independently living U.S. adults. The point system was based on their risk factors and survival rate at the end of 10 years.

    Their findings will be published Tuesday, March 5, in the Journal of the American Medical Association (JAMA).

    Calculating medical risk can be an inexact science, especially for older adults. Many factors from environmental to chronic diseases can help determine how long a person lives.

    "The most important thing we found was the risk factors that go into estimating shorter intermediate survival are very similar to risk factors that go into estimating the likelihood of longer-term survival," said first author Marisa Cruz, MD, a clinical fellow with the UCSF School of Medicine. "We also found that building a tool that clinicians can use to estimate that likelihood of longer-term survival requires considering many different types of risk factors.

  13. 14

    Celebrating Health Policy and Health Services Research at UCSF

    by UCSFPublicAffairs 285 views

    In 1972, the Philip R. Lee Institute for Health Policy Studies was founded at UCSF by Philip R. Lee, the University's third chancellor. It was the first multidisciplinary health services research group within a health sciences campus. Today, PRL-IHPS faculty are a diverse group that works to conduct, synthesize and translate research that can be applied to real-world policy arenas, program areas and practice settings.

    On February 27, 2013, a celebration was held in San Francisco's City Hall to acknowledge the health policy and health services research work at UCSF that was begun more than 40 years ago and continues to be vibrant and compelling today. A special part of the evening was this video that symbolized the event's theme of "honoring our roots and envisioning our future"; it features the Institute's founding director, Philip Lee, and founding associate director, Lewis Butler, and includes a number of past and current Institute faculty, staff and fellows.

  14. 15

    From Breast Tissue to Beating Heart Cells

    by UCSFPublicAffairs 1,022 views

    http://www.ucsf.edu/news/2013/03/13610/new-type-pluripotent-­cell-discovered-adult-breast-tissue

    To the surprise of the researchers, when the cells were differentiated into heart muscle, they even demonstrated the spontaneous beating seen in cardiomyocytes, or "beating heart" cells.

  15. 16

    Connecting the Dots: Mapping the Brain in a Common Form of Autism

    by UCSFPublicAffairs 1,662 views

    What you see here is state of the art for brain mapping today: a three-dimensional model of the wiring of a normal human brain, known as a "connectome", developed by Julia Owen, Pratik Mukherjee, Elliott Sherr and their colleagues at UC San Francisco and UC Berkeley.

    The larger and redder circles represent the "hubs" of the whole-brain network -- the regions with the greatest number of connections to other regions.

    Mapping the brain is emerging as the new frontier in science, and unlocking its mysteries promises to deliver fundamental new insights into human cognition and diseases, ranging from autism to depression to addiction to Alzheimer's. But the overwhelming complexity of the brain offers a significant challenge.

    The brain is an almost incomprehensible maze of long cells called neurons -- 100 billion of them in all -- each one making up to 10,000 connections with other neurons. Unlocking this complexity will take years, multidisciplinary approaches, new technology and hard work.

    The UCSF team used hospital MRIs and the mathematical tools of network analysis to trace the global connections within the brains of seven adults who have a genetic malformation that leaves them without a structure called the corpus callosum, which connects the left and right sides of the brain. This malformation is one of the top genetic causes of autism and was part of the mysterious brain physiology of Kim Peek, the remarkable savant portrayed by Dustin Hoffman in the 1987 movie "Rain Man."

    This is the first time that the connectome of a human brain malformation has been mapped, and it has revealed some of the unique anatomical features behind this genetic cause of autism.

    For more information, see: http://brain.ucsf.edu/

    Related Story: http://www.ucsf.edu/news/2013/02/13592/rain-man-brains-mappe­d-network-analysis

    Video animation by Pratik Mukherjee.
    Voiceover by Jason Socrates Bardi.
    @jasonbardi
    jason.bardi@ucsf.edu

    REFERENCE: NeuroImage 70, April 15, 2013 (340--355).

  16. 17

    The 2013 Flu Season: How to Protect Yourself

    by UCSFPublicAffairs 617 views

    Midway through the 2012-2013 flu season, this year has already been one of the worst in the last decade, according to the U.S. Centers for Disease Control and Prevention (CDC), and there have been more cases and more severe cases than usual.

    While the latest tracking data suggests that cases may have peaked nationally, there is still risk of catching the strains of influenza that are circulating nationally, and anyone who does get the flu is at risk of becoming severely ill, especially certain individuals who are most at-risk: the very young, the elderly, and immunocompromised people.

    But according to an influenza virus expert at UC San Francisco, there are still ways people can protect themselves.

    "Probably the first thing you should do is to get the vaccine," said Charles Chiu, MD, PhD, an assistant professor of laboratory medicine at UCSF and director of the UCSF-Abbott Viral Diagnostics and Discovery Center. "By administering the vaccine, the body will mount an antibody response to the virus that will prevent you from getting influenza."

    Other important ways to avoid catching or spreading the flu include careful and frequent hand-washing -- lathering for fifteen seconds under hot running water. Also, Chiu said, "It's really important that you try to not to go to school or work because there's a good possibility that you're contagious and that you may spread the disease to others."

    Chiu also highlighted that you cannot get the flu from influenza vaccine because the flu shot contains killed virus and the intranasal flu mist contains non-infectious virus that is cold-adapted to the nose and cannot replicate in the warmer temperatures of the rest of the body.

  17. 18

    Science in 10 years: Gov. Gray Davis Hopes for Cancer Advances, Fuel Efficient Vehicles

    by UCSFPublicAffairs 78 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    San Francisco Supervisor Scott Wiener hopes for new treatments - and a possible cure - for HIV/AIDS.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  18. 19

    Science in 10 years: Supervisor Wiener Hopes for HIV/AIDS Cure

    by UCSFPublicAffairs 143 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    San Francisco Supervisor Scott Wiener hopes for new treatments - and a possible cure - for HIV/AIDS.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  19. 20

    Science in 10 Years: Everyone Respects Scientific Method

    by UCSFPublicAffairs 46 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  20. 21

    Science in 10 Years: Chris Haskell at Bayer hopes for Better Experimental Medicine and Therapies

    by UCSFPublicAffairs 30 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  21. 22

    Science in 10 Years: Artificial Kidney, Renal Disease Cure, Diabetes Cure

    by UCSFPublicAffairs 278 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

  22. 23

    Science in 10 Years: Drug Delivery, Better Communication

    by UCSFPublicAffairs 71 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

  23. 24

    Science in 10 Years: Cures for Diseases, Cure for Multiple Sclerosis Polio, Cure Cancer

    by UCSFPublicAffairs 90 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

  24. 25

    Science in 10: UCSF Chancellor Sue Desmond-Hellmann - Cancer Therapies

    by UCSFPublicAffairs 100 views

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    As we look ahead to the next 10 years, UCSF Chancellor Sue Desmond-Hellmann, MD, MPH, hopes scientific research can advance to a point where she can one day tell a patient with cancer: "We cured what's wrong with you." Watch her video for a more comprehensive answer.

    What do you hope science accomplishes in the NEXT ten years? Share your thoughts in the comments section or on Twitter using the hashtag #next10science. Feel free to upload your own video response.

  25. 26

    Science in 10 Years: Lt. Gov. Gavin Newsom: We're Back in the Future Business

    by UCSFPublicAffairs 358 views

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    Lt. Gov. Gavin Newsom, who attended UCSF Mission Bay's 10th anniversary celebration, articulates his hope for science in the next 10 years. He talks about the importance of public-private partnerships and how UCSF Mission Bay is in the "future business," of investing in science and education.

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

  26. 27

    UCSF Mission Bay: A San Francisco Success Story

    by UCSFPublicAffairs 2,257 views

    A decade after opening its first research building at San Francisco's Mission Bay, UCSF has far surpassed its ambitious vision for a campus that today is an epicenter for science, health and hope.

    This year, UCSF celebrates a decade of discovery at Mission Bay -- a milestone that represents both a scientific renaissance and a significant revitalization of a once-blighted area in San Francisco's southeast sector.

    Since breaking ground in 1999, the development of the $3 billion Mission Bay campus is considered the single most important endeavor that UCSF has undertaken in its nearly 150-year history. UCSF Chancellor Susan Desmond-Hellmann, former San Francisco Mayor Willie Brown, Chancellor Emeritus J. Michael Bishop, UCSF Nobel laureate Elizabeth Blackburn, Mark Laret, CEO of UCSF Medical Center and UCSF Benioff Children's Hospital, and Regis Kelly, director of the California Institute for Quantitative Biosciences reflect on the success story that is UCSF Mission Bay.

  27. 28

    Stem Cells from Blood Vessels for Bone Marrow Transplant

    by UCSFPublicAffairs 215 views

    Ann Zovein, MD, studies stem cells with the goal of creating a more promising source of cells for bone marrow transplantation. The stem cells that spin off all blood types originate in the walls of blood vessels in the embryo. Zovein aims to find a way to use blood vessels as a source of stem cells that can be expanded in the lab to generate an off-the-shelf supply.

    http://www.ucsf.edu/news/2012/09/12726/nih-fosters-high-risk­-high-reward-innovation-ucsf

  28. 29

    Nerve Circuits and Schizophrenia

    by UCSFPublicAffairs 143 views

    Vikaas Sohal, MD, PhD, is exploring nerve-circuit-based ways to understand schizophrenia and related disorders, instead of conventionally focusing on excesses or deficiencies of particular chemicals in the brain.

    http://www.ucsf.edu/news/2012/09/12726/nih-fosters-high-risk­-high-reward-innovation-ucsf

  29. 30

    Lung Cancer — Overcoming Drug Resistance

    by UCSFPublicAffairs 154 views

    Trever Bivona, MD, PhD, uses new techniques to identify more advanced treatment strategies to target lung cancers that continually evolve genetically to develop drug resistance.

    http://www.ucsf.edu/news/2012/09/12726/nih-fosters-high-risk­-high-reward-innovation-ucsf

  30. 31

    Genome, Proteome and Now, the Interactome

    by UCSFPublicAffairs 225 views

    Xiaokun Shu, PhD, is tackling the challenge of mapping the "interactome," an atlas of how proteins interact with one another to drive and control biological events.

    http://www.ucsf.edu/news/2012/09/12726/nih-fosters-high-risk­-high-reward-innovation-ucsf

  31. 32

    Science in 10 Years: New Startups, Delivering Drugs

    by UCSFPublicAffairs 58 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  32. 33

    Science in 10 Years: Treatment and a Cure for AIDS and HIV

    by UCSFPublicAffairs 98 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  33. 34

    Science in 10 Years: Cures for Disease and Innovation from Big Pharma

    by UCSFPublicAffairs 56 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  34. 35

    Science in 10 Years: Clean Water and Clean Energy

    by UCSFPublicAffairs 56 views

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    http://www.ucsf.edu/news/decade-discovery-ucsf-mission-bay

  35. 36

    Science in 10 Years: Vaccine for HIV

    by UCSFPublicAffairs 79 views

    Ten years ago, UCSF opened the doors to a new research campus at Mission Bay, launching a vibrant "biotech ecosystem" for San Francisco.

    What do you hope science accomplishes in the NEXT ten years? Share your dreams in the comments or on Twitter using the hashtag #next10science.

  36. 37

    Performing Spinal Surgeries with Two Attending Surgeons

    by UCSFPublicAffairs 660 views

    Two heads are better than one, as the saying goes -- and a new study by a duo at the University of California, San Francisco (UCSF) demonstrates how having two attending surgeons in the operating room during spinal surgeries can benefit patients in multiple ways.

    Most spinal surgeries in the United States are performed by teams led by a single attending surgeon -- one top-level doctor who has completed medical school, residency and other specialized training.

    In 2007, two spinal surgeons in the Departments of Neurological Surgery and Orthopedic Surgery joined forces and began doing certain complex, high-risk procedures together, and now they have published their findings on the benefits of having them both in the operating room.

    In this video, UCSF neurosurgeon Christopher Ames, MD, who led the study with orthopedic surgeon Vedat Deviren, MD. describes the procedure considered in the study: pedicle subtraction osteotomy, a surgery that realigns the spine in cases of very severe deformities, many of which arise from alignment complications of prior surgery and severe degenerative spinal arthritis.

    Read more: http://ucsf.edu/news/2013/01/13402/complex-spinal-surgeries-­two-attending-physicians-instead-one-benefit-patients

    Video by Jason Socrates Bardi
    Animation by Chris Ames, A.Bokelman, and K.Probst/Xavier Studios
    Photos by Susan Merrell

  37. 38

    San Francisco, UCSF Celebrate Mission Bay Science, Patient Care, and Education

    by UCSFPublicAffairs 1,139 views

    What do you hope science achieves in the next 10 years? Leave your response in the comments.

    Ten years ago, UCSF opened the doors of its first research building at Mission Bay, launching a new community in an area of abandoned rail yards. Today, the area has developed into a "bioscience ecosystem," with UCSF -- the nation's largest public biomedical research university -- as its hub. Around the campus is a growing cadre of life science companies, startups and venture capital firms that are translating the university's research into companies and products to improve health worldwide. Also underway is the state-of-the-art UCSF Medical Center at Mission Bay, which will open in February 2015 and set a new standard in patient-centered care, safety and translating discoveries into advances in treatment for children, women and cancer patients.

  38. 39

    The Singing Pathologist

    by UCSFPublicAffairs 2,589 views

    Arie Perry, MD, the director of neuropathology at the University of California, San Francisco (UCSF) is an expert at recognizing the subtle signs of brain cancer, Parkinson's, Alzheimer's and other neurological diseases under the microscope.

    He also teaches pathology to medical residents, medical students and other professionals at UCSF, and one technique he has developed over his career is to put some of the hard-to-learn facts to music as a way of helping his students learn.

    Here he sings the "Meningiomas" song and discusses how he started down this road years ago. Also interviewed is S. Andrew Josephson, MD, who directs the class "Brain Mind and Behavior" for UCSF medical students who learn about subjects like meningioma-type brain tumors with the help of Perry's songs.

    "From the surface of the brain and the arachnoidal membrane
    Grows a dural neoplasm, meningioma is its name
    As a tumor of adults, with sharp margins and slow growth,
    It may require the gamma knife, or surgery alone."

    "Though most are low-grade, with a bland histology,
    There's an aggressive subset, with significant morbidity
    Atypical meningiomas, recur quite frequently
    Anaplastic cases have a high mortality"

    Video by Jason Socrates Bardi
    jason.bardi@ucsf.edu
    @jasonbardi

  39. 40

    Commercial Space Travel Carries Implications for Health

    by UCSFPublicAffairs 313 views

    http://www.ucsf.edu/news/2012/12/13309/commercial-space-trav­el-carries-implic...

    UCSF-Led Research Team Suggests Developing Health Screening Standards for Citizen Astronauts

    Just a half-century after the first human ventured into space, commercial space travel -- or "space tourism" -- is quickly becoming a reality. A new UCSF study looks at the health implications of flying into outer space and suggests establishing health screening standards for private citizens who want to blast off.

    "We all have questions from patients related to air travel," said lead author S. Marlene Grenon, MD, MS, assistant professor of surgery at the UCSF Division of Vascular and Endovascular Surgery, and a researcher at the San Francisco VA Medical Center. "In the short future, we may be getting questions from our patients about space travel."

    Research on the impact of space on the human body started in 1957, when the U.S.S.R. initiated the space race with the launch of Sputnik 1, the first human-made object to be placed in orbit. Over the years, UCSF researchers have studied the impact of space on humans showing the effects -- both physically and mentally -- are profound.

    "In a zero-gravity outer-space environment, humans go through very unique physiological changes," Grenon explained. "They experience bone loss, muscle atrophy, increased risk of certain heart problems, decrease in immune function, kidney stones and motion sickness. These significant changes in the body and how it functions need to be considered."

    The study, published Thursday in the British Medical Journal, highlights the lack of understanding most physicians have about the impact of space travel on the body.

    Right now, there are no strict criteria on how to advise consumers about the health implications of commercial space travel. The researchers suggest having health screening standards as it becomes more popular.

    "The changes that occur in zero gravity happen for several reasons," Grenon said. "This includes a volume redistribution towards the chest and head, decrease use of the lower extremities, and the lack of gravitational stimuli on the cells."

    Millie Hughes-Fulford, PhD, a UCSF professor of biochemistry and biophysics and a medical investigator at the San Francisco VA Medical Center, has experienced first-hand the changes and challenges to the human body while in space. A molecular biologist, she was the first woman to travel into space as a working scientist on board the shuttle Columbia in 1991.Since then she become a world leader in exploring what happens to the immune system and bone cells when thrust into outer space.

    "It feels like you're on top of a roller coaster while you're in outer space. That feeling, in the pit of your stomach, is what you'll experience the entire time," said Hughes-Fulford, the study's senior author and one of the first female NASA astronauts. "You must check with your doctor to see if your heart and other vital organs are up for this type of adventure."

    Video shot and edited by Leland Kim. Space footage courtesy of NASA.

  40. 41

    Acute Kidney Injuries: A Growing U.S. Epidemic

    by UCSFPublicAffairs 268 views

    Severe acute kidney injuries are becoming more common in the United States, rising 10 percent per year and doubling over the last decade, according to a retrospective study at the University of California, San Francisco (UCSF).

    The study, to be published online this week in the Journal of the American Society of Nephrology, analyzed information from a national database that monitors all causes of hospitalizations and used this data to estimate the total number of acute kidney injuries in the United States that were severe enough to require a patient to be placed on dialysis.

    In this video, UCSF faculty discuss the new study and the problem of kidney disease in the United States today.

    Read more: http://www.ucsf.edu/news/2012/12/13267/severe-acute-kidney-i­njuries-rise-rapidly-nationwide

    Video by Jason Socrates Bardi

  41. 42

    Building a Microscope with LEGOs and an iPhone

    by UCSFPublicAffairs 1,654 views

    http://www.ucsf.edu/news/2012/12/13250/design-science-ucsf-p­roject-applies-innovative-thinking-research
    An experimental design project at UCSF has created a smartphone microscope made out of specialized LEGO blocks. The invention was the result of students aiming to revolutionize the way we approach scientific research.

  42. 43

    Virtual Tour - UCSF Medical Center at Mission Bay

    by UCSFPublicAffairs 588 views

    Opening in 2015, these three new hospitals for children, women, and cancer patients will help to define the future of health care. Be among the first to "step" inside -- take our virtual tour and see the construction of this remarkable new Medical Center as it proceeds at a rapid pace.

  43. 44

    Stem Cells for Regenerative Medicine

    by UCSFPublicAffairs 2,030 views

    http://www.ucsf.edu/news/2012/11/13181/stem-cell-banks-envis­ioned-regenerative-medicine
    Stem cell banks might one day be used to meet the tissue-transplant needs of most of the population. Just as there are universal blood donors, cells from universal donors could be used to develop induced pluripotent stem cells (iPS cells) or adult stem cells for use in repairing the nervous system, the heart or other organs.

    Off-the-shelf cell lines could be made available for recipients in a timely way, with matching likely to lower risk of transplant rejection. UCSF stem cell scientist Bruce Conklin, MD, discusses.

  44. 45

    UCSF Helen Diller Family Comprehensive Cancer Center Showcase 2012: Opening Plenary Session

    by UCSFPublicAffairs 226 views

    The UCSF Helen Diller Family Comprehensive Cancer Center Showcase 2012 opening plenary session includes presentations on the latest information in cancer research by Chancellor Susan Desmond-Hellmann, MD, MPH, Frank McCormick, PhD, FRS, director of the UCSF Helen Diller Family Comprehensive Cancer Center, and Elliott Sigal, MD, PhD, executive vice president and chief scientific officer and president, Research and Development, Bristol-Myers Squibb.
    .

  45. 46

    UCSF - Helen Diller Family Comprehensive Cancer Center

    by UCSFPublicAffairs 152 views

    Learn more about how UCSF's expert team is advancing cancer care and research worldwide.

  46. 47

    PTSD in Women and the Role of Fear Conditioning

    by UCSFPublicAffairs 876 views

    http://www.ucsf.edu/news/2012/11/13155/gender-differences-pt­sd-risk-may-be-due-heightened-fear-conditioning-women
    Gender differences in PTSD risk may be due to a heightened rear response in Women, according to a UCSF study in the Oct. 26, 2012 edition of the Journal of Psychiatric Research.

    In a study of individuals with PTSD symptoms, researchers found that the women were more likely than the men to develop a stronger fear response, and -- once conditioned to respond fearfully -- more likely to have stronger responses to fear-inducing stimuli.

    "Differences in the learning of fear may be one mechanism that may be important in the development of PTSD," said Sabra Inslicht, PhD, a UCSF assistant professor of psychiatry at the San Francisco VA Medical Center.

  47. 48

    What the Tobacco Companies Didn't Warn You About

    by UCSFPublicAffairs 1,140 views

    http://www.ucsf.edu/news/2012/11/13151/cigarette-pack-health­-warning-labels-us-lag-behind-world
    UCSF's Stanton A. Glantz, PhD, professor of medicine and director of the UCSF Center for Tobacco Control Research and Education, discusses the evolution of health warning labels on cigarette packs.

    Health warning labels have adorned cigarette packages since 1966, when they first appeared in the United States. And in the decades since, they have spread steadily around the world -- in many instances, becoming more strongly worded, more prominently placed and more graphic over time.

    According to a new study by UCSF researchers, the evolution of labeling laws country by country has proceeded in fits and starts, thanks largely to efforts by the tobacco industry to block their spread around the world from the start.

    Using the 80 million pages of previously secret internal documents from major tobacco companies, the team developed a chronology of this half-century battle, which is described in an article published last month in the journal Tobacco Control.

    Video by Jason Socrates Bardi
    email: jason.bardi@ucsf.edu
    twitter: @jasonbardi

  48. 49

    Unique UCSF Program for Amputee Athletes Gains Momentum

    by UCSFPublicAffairs 779 views

    http://www.ucsf.edu/news/2012/11/13146/amputee-athletes-maxi­mize-their-physical-potential-ucsf
    More than 60 amputee athletes participating in UCSF's Amputee Comprehensive Training (ACT) program, the first civilian program of its kind designed to assist amputees in maximizing their physical potential through a broad range of resources offered by the UCSF Department of Orthopaedic Surgery.

    "We are providing services beyond therapy," said Matthew Garibaldi, CPO, director of the Orthotics & Prosthetics Centers at UCSF. "We have instrument and data analysis to assess a patient's running stride and gait. We also have certified trainers on staff who are addressing core instabilities, necessary strength training, in addition to prosthetic experts who round out a truly comprehensive training experience for our patients."

    The ACT program has quickly become popular, attracting athletes as far away as North Carolina and the Bahamas.

    "It's been a pretty thrilling day to be here," said Creighton Wong, one of the participants. "There are a lot of familiar faces in terms of accomplished athletes and world class athletes, but just as importantly, I'm seeing many new faces, new amputees, who are learning how to walk, or run for the very first time. To be able to pass that knowledge on to them is rewarding and exciting."

    Video shot and edited by Leland Kim.

  49. 50

    Heart Failure Drug Shows Promise in Phase III Clinical Trial

    by UCSFPublicAffairs 288 views

    Hospitalized heart failure patients who received the drug, serelaxin, in a phase III clinical trial had fewer disease symptoms and as a group experienced 37 percent fewer deaths over six months, according to results of a new study.

  50. 51

    UCSF Global Health Presents '7 Billion Well: Re-imaging Global Health'

    by UCSFPublicAffairs 172 views

    TEDx San Francisco and UCSF Global Health Sciences are uniting forces for the first time ever to showcase "7 Billion Well," a global health-focused TEDx event on Nov. 10, 2012.

    The goal is to create a community of diverse individuals who converse on ideas worth sharing and drive idea formation to innovate, revolutionize, and change the world in the global health sciences realm. Crucial questions will be explored addressing the cutting-edge intersection of scientific research, medicine, technology, and industry in global health in the spirit of celebrating traditions that include the healing and performing arts, through music, dance, and media.

    Those who can't experience TEDxSF "7 Billion Well: Re-imaging Global Health" in person, can join online for the free, live webcast at tedxsf.org.

  51. 52

    Rock Climber Defies Odds, Thanks to UCSF's Top Lung Transplant Program

    by UCSFPublicAffairs 970 views

    http://www.ucsf.edu/news/2012/11/13055/rock-climber-exceeds-­expectations-after-double-lung-transplant
    Rowan Jimenez cautiously climbed 10,911 feet to the top of Cathedral Peak, one of the highest points at Yosemite National Park. The 42-year-old rock climber and rock musician has traversed this spot many times before, but this particular attempt was different. It was a triumphant return on the two-year anniversary of his double lung transplant surgery in 2008.

    "My friends thought I was crazy," Jimenez said. "But I needed to do it. I needed to know that I still had my old life. I didn't want to be content to just be sitting on a couch. That wouldn't have worked for me."

    Jimenez was diagnosed with scleroderma, an autoimmune disease, in early 2008 after he constantly experienced shortness of breath.

    "I just thought I was getting old," he said. "I didn't realize it was something more serious."

    The once energetic rock performer was tired and had difficulty catching his breath. He was in the early stage of lung failure.

    Jimenez went to UCSF's Lung Transplant Program, one of the top programs in the country, according to the Scientific Registry of Transplant Recipients (SRTR). UCSF is ranked second out of 70 for "higher than expected" outcomes based on complex risk factors.

    Video shot and edited by Leland Kim.

  52. 53

    Asthma Researcher Makes Rare Leap from Graduate School to UCSF Principal Investigator

    by UCSFPublicAffairs 256 views

    http://www.ucsf.edu/news/2012/11/13070/asthma-researcher-mak­es-rare-leap-graduate-school-ucsf-principal-investigator-and
    Most young scientists fresh out of graduate school are content to begin a post-doctoral fellowship, working for an established faculty member. But for Christopher Allen, PhD, award-winning research in asthma meant the fast-track onto UCSF's faculty.

  53. 54

    The Heart of a Champion

    by UCSFPublicAffairs 1,288 views

    As 13-year-old Sean White stood on stage to receive a medal of courage from Gen. Colin Powell, the image of the healthy, active boy belied the challenges he overcame to earn the amazing honor.

    Sean was born with Shone's Complex, a congenital heart disease that's often fatal for infants, and underwent three life-saving heart surgeries within the first three years of his life. Not only has he survived the ordeal and other complications, Sean is now an athlete in baseball, soccer and basketball.

    Powell, former US secretary of state and chairman of the Joint Chiefs of Staff, honored Sean with a special "UCSF Gen. Colin Powell Medal of Courage" on Sept. 20 during a benefit concert for the UCSF Benioff Children's Hospital at the Bill Graham Civic Auditorium in San Francisco. The event, hosted by Salesforce.com as part of its Dreamforce conference, raised $4.3 million for the completion of the new UCSF Benioff Children's Hospital, which is scheduled to open at Mission Bay in February 2015.

    Sean's journey to sharing the stage with a four-star general was a long one.

    Shone's Complex causes obstructions to the left side of the heart -- both the inflow of the heart coming from the atrium to the ventricle, and the outflow of the heart from the ventricle out to the aorta and around the aorta.

    "It depends on how severe the obstruction is," said David Teitel, MD, medical director of the Pediatric Heart Center at the UCSF Benioff Children's Hospital. "But most children with Shone's Complex have critical obstruction as infants and wouldn't survive without an intervention in the first year of life."

    Video shot and edited by Leland Kim.

  54. 55

    UCSF Convenes First-Ever Primary Care Summit

    by UCSFPublicAffairs 333 views

    http://www.ucsf.edu/news/2012/10/12981/first-ever-partners-p­rimary-care-summit-shares-lessons-field
    The first-ever UCSF and Partners Primary Care Summit brought key players together to discuss how to improve patient-focused care in San Francisco as part of national health reform. The summit drew more than 160 health professionals who work at three major health delivery systems in San Francisco in which UCSF is involved: the San Francisco Department of Public Health, UCSF Medical Center and the San Francisco Veterans Affairs Medical Center.

    Kevin Grumbach, MD, chair and professor in UCSF Department of Family and Community Medicine, and Catherine Lucey, MD, vice dean for education in the UCSF School of Medicine, organized the meeting bringing leaders in primary care practice and education together from all three systems to:
    · Learn from each other about goals, strategies and challenges as they transform primary care;
    · Share best practices and pragmatic tools to advance a collective aspiration toward high performing, career-satisfying primary care;
    · Plan how to transform and align UCSF curricula and training with the new models of primary care being deployed in clinical practices; and
    · Promote ongoing collaboration in primary care between all three sites/systems.

  55. 57

    UCSF Joins "It Gets Better" Project (Emmy® Award Nominee)

    by UCSFPublicAffairs 2,646 views

    This video is nominated for a 2012-13 regional Emmy® Award in the category of "Community/Public Service Spot Announcement" by the National Academy of Television Arts & Sciences San Francisco/Northern California Chapter.

    http://www.emmysf.tv/images/emmy13%20nomination%20press%20re­lease.pdf

    Members of the UCSF LGBTQ community joined together to create this heartfelt, singular message of hope for at-risk youth on National Coming Out Day (October 11, 2012). The following resources for LGBTQ people were featured in the video:

    It Gets Better Project http://www.itgetsbetter.org/
    The National Suicide Prevention Lifeline 800-273-TALK (8255) http://www.suicidepreventionlifeline.org/
    The Trevor Project 866-4-U-TREVOR (866-488-7386) http://www.thetrevorproject.org/
    UCSF Office of Diversity and Outreach 415-476-7700 http://diversity.ucsf.edu/
    San Francisco LGBT Center 415-865-5555 http://www.sfcenter.org/
    Dimensions Queer Youth Health Clinic 415-934-7716 http://www.dimensionsclinic.org/
    Seneca Center 415-642-5968 www.senecacenter.org

    The following members of the UCSF LGBTQ community were featured in the video (in the order of appearance): Barbara French, Charles Bennett, Sneha Oberoi, Ethan Leavy, Timothy Mok, Danielle Castro, Will Hocker, Maureen Royer, Kevin Eisenmann, Angel Ventura, Paul Day, Molly Steen, Rebecca Jackson, Tim Kelly, Leland Kim, Sarah Marshall, Christin Chong, Ron James, James Betbeze, Joanne Keatley, Enzo Patouhas, Brian Turner, Patty Robertson, Jason Rock, Michael Towne, Mike Eccles, Amber Fitzsimmons, James Moser, Joel Moncada, Stuart Gaffney, Yavante Thomas-Guess, and Will McCall.

    Video shot, written, produced and edited by Leland Kim.

  56. 58

    Top Health Sciences Students Choose UCSF

    by UCSFPublicAffairs 2,905 views

    UCSF first-year students gathered in the Millberry Union gym for a festive orientation. They got a chance to meet other students and listen to an address by Chancellor Susan Desmond-Hellmann. Students from the School of Medicine, School of Dentistry, School of Pharmacy, School of Nursing, and Graduate Division were in attendance.

    Video shot and edited by Leland Kim.

    Do you have UCSF spirit? Go to http://www.facebook.com/ucsf and "like" our page. Submit a "UCSF Spirit" photo. Top 3 photos will win a prize. The grand prize is an iPad 2. Upload photos until 11:59 pm PST on October 12th. Voting is from 12 midnight October 13 until 11:59 pm October 19. Winners announced on October 20.

  57. 59

    Gladstone, UCSF Leaders Reflect on Shinya Yamanaka's Nobel Prize

    by UCSFPublicAffairs 5,421 views

    http://www.ucsf.edu/news/2012/10/12926/ucsf-and-gladstone-ce­lebrate-shinya-yamanakas-nobel-prize-medicine
    Gladstone and UCSF leaders celebrated news of the Nobel Prize for Yamanaka, MD, PhD, a senior investigator at the UCSF-affiliated Gladstone Institutes and a UCSF professor of anatomy, who discovered a way to reprogram ordinary human skin cells into stem cells that could be used to grow tissues for organ transplantation and for other medical applications. His discovery came nearly 50 years after John Gurdon, PhD, of the Gurdon Institute in Cambridge, England -- with whom Yamanaka shares the Nobel Prize -- showed in frogs that the genetic program of a mature cell could be "reset" to its embryonic state.

    The stem cell discovery by Shinya Yamanaka that won the 2012 Nobel Prize in Medicine not only has transformed the research landscape, but it has revolutionized medicine over the coming decade, colleagues at the Gladstone Institutes and UCSF say.

  58. 60

    UCSF Chancellor Provides Update on Strategic Plan

    by UCSFPublicAffairs 393 views

    http://www.ucsf.edu/news/2012/09/12807/amid-challenges-chanc­ellor-optimistic-about-ucsf-leadership-health-sciences
    In her third annual State of the University address since becoming the ninth UCSF chancellor in 2009, Susan Desmond-Hellmann, MD, MPH, praised the past year's progress toward achieving UCSF's 2014-2015 Strategic Plan. The plan spells out UCSF's vision to be the world's preeminent health sciences innovator and outlines five goals. During her address, Desmond-Hellmann invites members of her leadership team to cite progress toward achieving the five goals, which are to provide unparalleled care to patients, improve health worldwide through innovative science, attract and support the most talented and diverse trainees in the health sciences, be the workplace of choice of diverse, top-tier talent and to create a financial sustainable enterprisewide business model in support of UCSF's public mission.

  59. 61

    Donating Your Body to Science

    by UCSFPublicAffairs 2,015 views

    Since the earliest days of medicine, the complex study of human anatomy has been an integral part of health science training and research. For more than 60 years, the UCSF Willed Body Program has overseen the donation of bodies for medical education and research. Andrew Corson, director of the UCSF Willed Body Program, talks about the program, which is the largest such program in the state, receiving approximately 400 donated bodies a year. Cadavers donated to UCSF are supplied to a number of programs including UCSF's School of Medicine, School of Dentistry and School of Pharmacy, as well as the orthopedics, ophthalmology, otolaryngology and physical therapy departments. Additionally, UCSF provides cadavers to other UC campuses and approximately 50 non-UC schools in Northern California, research groups and emergency medical education programs. Each entity must adhere to strict protocol guidelines, and each application is vetted by the UCSF Anatomical Material Review Committee.

  60. 62

    San Francisco: Center of Innovation

    by UCSFPublicAffairs 1,307 views

    http://www.ucsf.edu/news/2012/10/12875/san-francisco-becomes­-leading-center-innovation-health-care-and-biosciences
    San Francisco is a leading center of innovation in health care and biosciences in the world. The combined economic impact of hospital, biomedical research and health sciences education spending is $16.7 billion and together they generate more than 100,000 jobs per year -- almost one in five jobs in the City and County of San Francisco. UCSF Chancellor Susan Desmond-Hellmann, MD, MPH, Sue Currin, RN, MSN, president of the Hospital Council of Northern California and CEO of San Francisco General Hospital and Trauma Center, and Terry Hermiston, PhD, vice president of Bayer Healthcare Pharmaceuticals and the U.S. Innovation Center, reflect on why San Francisco has been successful in fueling the economy, ensuring the health of its citizens and conducting groundbreaking research aimed at improving health worldwide.

  61. 63

    UCSF Leaders and Scholars Reflect on First-Generation College Experiences

    by UCSFPublicAffairs 497 views

    The path to college isn't always clear, but more and more people are forging their way through higher education. At UCSF, this "invisible community" is bigger than you may think.

    In this video, some of UCSF's leaders and scholars -- Joseph Castro, PhD, vice chancellor of Student Academic Affairs; Don Ng, MD, associate director of the General Medicine Clinic; Lilliam Pinzon, DDS, MS, MPH, assistant adjunct professor in the School of Dentistry; Brian Alldredge, PharmD, associate dean for School of Pharmacy's Academic Affairs; and Betty Booker, PhD, postdoctoral scholar in the School of Pharmacy -- reflect on their pioneering academic journeys and offer some advice on how to thrive at this world-class institution.

    If you're a UCSF student who's the first in your family to attend college or grad school, check out the First-Generation College Initiative and join the Facebook community.

    http://saa.ucsf.edu/vice-chancellor-initiatives/first-genera­tion-college
    http://www.facebook.com/firstgenUCSF

    Video shot and edited by Leland Kim.

  62. 64

    New Anatomy Lab at UCSF Prepares Next Generation of Clinicians

    by UCSFPublicAffairs 8,746 views

    http://www.ucsf.edu/news/2012/09/12775/new-anatomy-learning-­center-prepares-next-generation-clinicians
    The days of carrying hefty, 1,500-page Gray's Anatomy textbooks may be long gone, but not much more has changed over the decades in how medical students learn anatomy - until now. Students at the University of California, San Francisco (UCSF) have just begun studies in a new, state-of-the-art anatomy learning center equipped with interactive iPad textbooks, giant video displays and roving cameras that will allow them to observe, discover, and come to understand, in a new way, the complex architecture of the human body.

  63. 65

    Donativo de $20 Millones para un nuevo Centro de Salud Global en UCSF

    by UCSFPublicAffairs 65 views

    http://www.ucsf.edu/news/2012/09/12746/global-health-launch-­hub-ucsf-20-million-gift
    La Universidad de California, San Francisco ha recibido una donación de 20 millones de dolares para construir un centro nuevo de Ciencias de la Salud Global en el campus de Mission Bay de UCSF. Este donativo por Chuck Feeney y The Atlantic Philanthropies permitirá, por vez primera, tener una magnifico edificio para albergar a científicos y estudiantes de Salud Global en uno de los principales centros de biomedicina del mundo entero.

    Para más detalles sobre las Ciencias de la Salud Global, el donativo, y la visión de UCSF Mission Bay, visite a www.ucsf.edu.

    Fotos por cortesía de UCSF Global Health Sciences. Esquemas del edificio por cortesía de la firma de arquitectura WRNS Studios. Vídeo editado por Leland Kim.

  64. 66

    $20 Million Gift Launches Global Health Hub at UCSF

    by UCSFPublicAffairs 1,140 views

    http://www.ucsf.edu/news/2012/09/12746/global-health-launch-­hub-ucsf-20-million-gift
    UC San Francisco has received a $20 million gift from philanthropist Chuck Feeney through his charitable foundation, The Atlantic Philanthropies, to build a new hub for Global Health Sciences at the UCSF Mission Bay campus. The gift will enable UCSF, for the first time, to have one physical location for global health researchers, scientists and students at one of the world's foremost bioscience campuses.

    The gift brings Feeney's total support of UCSF Mission Bay to $295 million, making him the single greatest contributor to any campus in the University of California system. For more details on Global Health Sciences and the vision for Mission Bay, visit www.ucsf.edu.

    Photos courtesy of UCSF Global Health Sciences. Building schematics courtesy of architecture firm WRNS Studios. Video shot and edited by Leland Kim.

  65. 67

    The Microscopic Motors of Life

    by UCSFPublicAffairs 1,682 views

    http://www.ucsf.edu/news/2012/09/12693/ucsf-professor-receiv­es-2012-lasker-award
    UCSF's Ronald Vale, PhD, discusses efforts beginning in the early 1980s that uncovered how cytoskeletal motor proteins work — the basis of muscle contractions and heartbeats and of transport within cells. Along with James Spudich, PhD, of Stanford University, and Michael Sheetz, PhD, of Columbia University, Vale won the 2012 Albert Lasker Basic Medical Research Award.

    Here he describes the discovery of kinesin, a protein machine that is about one-millionth of an inch across. Kinesins and other motor proteins are also associated with a number of human diseases, including cardiomyopathies, which affect the ability of the heart's muscles to contract and are associated with sudden death in athletes, and neuropathies, which can be produced by impaired transport in nerve cells.

    http://www.ucsf.edu/news/2012/09/12693/ucsf-professor-receiv­es-2012-lasker-award

    Video by Jason Socrates Bardi, @jasonbardi

  66. 68

    How to Survive a Hantavirus

    by UCSFPublicAffairs 6,497 views

    http://www.ucsf.edu/news/2012/08/12648/hantavirus-be-careful­-not-fearful
    UCSF's Charles Chiu, MD, PhD, discusses hantavirus, a potentially fatal virus transmitted by rodents such as deer mice, which is making news following an outbreak at a popular tourist area of Yosemite National Park. The recent cases are a reminder for campers to be cautious, but not necessarily fearful, said Chiu.

    Previous hantavirus cases in Yosemite had originated at higher elevations, which are favored by the deer mouse that carries the virus, said Chiu, who directs the UCSF-Abbott Viral Diagnostics and Discovery Center. Other rodents, including house mice, are rarely if ever carriers of the virus.

    Video by Jason Socrates Bardi
    Twitter: @jasonbardi

  67. 69

    A Genetic Marker of Increased Risk for Brain Cancer

    by UCSFPublicAffairs 522 views

    http://www.ucsf.edu/news/2012/08/12579/ucsf-mayo-team-discov­ers-genomic-variant-increases-risk-brain-tumors
    People who carry a "G" instead of an "A" at a specific spot in the sequence of their genetic code have roughly a six-fold higher risk of developing certain types of brain tumors, according to a study by researchers at the University of California, San Francisco (UCSF) and Mayo Clinic.

    In this video,UCSF geneticists Margaret Wrensch, PhD, and John Wiencke, PhD, discuss findings published in the journal Nature Genetics that could help researchers identify people at risk of developing certain subtypes of gliomas, which account for about 4,600 of the 23,000 brain cancers newly diagnosed annually in the US. This information could lead to better surveillance, diagnosis and treatment.

    Based on their findings, the scientists already are starting to think about clinical tests that could tell patients with abnormal brain scans what kind of tumor they have, by simply testing their blood.

  68. 70

    UCSF Expert Answers the Question: Does "Blade Runner" Oscar Pistorius Have a Competitive Edge?

    by UCSFPublicAffairs 460 views

    Matthew Garibaldi, director of the UCSF Orthotic & Prosthetic Center, and amputee athlete Geoff Turner answer the question of whether or not South African Olympian Oscar Pistorius has a competitive edge with his Ossur carbon fiber running blades compared to his two-legged competitors.

  69. 71

    Health Reform in Aftermath of Supreme Court Ruling PART 5

    by UCSFPublicAffairs 48 views

    UCSF and UC Hastings experts convened to discuss the impact of the U.S. Supreme Court ruling on the Patient Protection and Affordable Care Act, President Obama's landmark domestic policy.

    The Supreme Court's decision has wide-reaching consequences for health care in America. "What Now? Health Reform in the Aftermath of the Supreme Court Decision," features experts who discuss the legal significance of the decision and the practical implications for health care.

    The forum is sponsored by the UCSF Philip R. Lee Institute for Health Policy Studies, one of the nation's premier centers for health policy and health services research, in conjunction with UC Hastings and the UCSF-UC Hastings Consortium on Law, Science, and Health Policy.

    Part 1 - David Faigman, JD, director UCSF/UC Hastings Consortium, John F. Digardi Distinguished Professor of Law, UC Hastings
    Part 2 - Jaime King, JD, PhD, associate directors, UCSF/UC Hastings Consortium, professor, UC Hastings
    Part 3 - Andrew Bindman, MD, professor of medicine, health policy, epidemiology and biostatistics, UCSF
    Part 4 - Josh Adler, MD, chief medical officer, UCSF Medical Center and UCSF Benioff Children's Hospital
    Part 5 - Q&A with Audience

  70. 72

    Health Reform in Aftermath of Supreme Court Ruling PART 4

    by UCSFPublicAffairs 35 views

    UCSF and UC Hastings experts convened to discuss the impact of the U.S. Supreme Court ruling on the Patient Protection and Affordable Care Act, President Obama's landmark domestic policy.

    The Supreme Court's decision has wide-reaching consequences for health care in America. "What Now? Health Reform in the Aftermath of the Supreme Court Decision," features experts who discuss the legal significance of the decision and the practical implications for health care.

    The forum is sponsored by the UCSF Philip R. Lee Institute for Health Policy Studies, one of the nation's premier centers for health policy and health services research, in conjunction with UC Hastings and the UCSF-UC Hastings Consortium on Law, Science, and Health Policy.

    Part 1 - David Faigman, JD, director UCSF/UC Hastings Consortium, John F. Digardi Distinguished Professor of Law, UC Hastings
    Part 2 - Jaime King, JD, PhD, associate directors, UCSF/UC Hastings Consortium, professor, UC Hastings
    Part 3 - Andrew Bindman, MD, professor of medicine, health policy, epidemiology and biostatistics, UCSF
    Part 4 - Josh Adler, MD, chief medical officer, UCSF Medical Center and UCSF Benioff Children's Hospital
    Part 5 - Q&A with Audience

  71. 73

    Health Reform in Aftermath of Supreme Court Ruling PART 3

    by UCSFPublicAffairs 28 views

    UCSF and UC Hastings experts convened to discuss the impact of the U.S. Supreme Court ruling on the Patient Protection and Affordable Care Act, President Obama's landmark domestic policy.

    The Supreme Court's decision has wide-reaching consequences for health care in America. "What Now? Health Reform in the Aftermath of the Supreme Court Decision," features experts who discuss the legal significance of the decision and the practical implications for health care.

    The forum is sponsored by the UCSF Philip R. Lee Institute for Health Policy Studies, one of the nation's premier centers for health policy and health services research, in conjunction with UC Hastings and the UCSF-UC Hastings Consortium on Law, Science, and Health Policy.

    Part 1 - David Faigman, JD, director UCSF/UC Hastings Consortium, John F. Digardi Distinguished Professor of Law, UC Hastings
    Part 2 - Jaime King, JD, PhD, associate directors, UCSF/UC Hastings Consortium, professor, UC Hastings
    Part 3 - Andrew Bindman, MD, professor of medicine, health policy, epidemiology and biostatistics, UCSF
    Part 4 - Josh Adler, MD, chief medical officer, UCSF Medical Center and UCSF Benioff Children's Hospital
    Part 5 - Q&A with Audience

  72. 74

    Health Reform in Aftermath of Supreme Court Ruling PART 2

    by UCSFPublicAffairs 39 views

    UCSF and UC Hastings experts convened to discuss the impact of the U.S. Supreme Court ruling on the Patient Protection and Affordable Care Act, President Obama's landmark domestic policy.

    The Supreme Court's decision has wide-reaching consequences for health care in America. "What Now? Health Reform in the Aftermath of the Supreme Court Decision," features experts who discuss the legal significance of the decision and the practical implications for health care.

    The forum is sponsored by the UCSF Philip R. Lee Institute for Health Policy Studies, one of the nation's premier centers for health policy and health services research, in conjunction with UC Hastings and the UCSF-UC Hastings Consortium on Law, Science, and Health Policy.

    Part 1 - David Faigman, JD, director UCSF/UC Hastings Consortium, John F. Digardi Distinguished Professor of Law, UC Hastings
    Part 2 - Jaime King, JD, PhD, associate directors, UCSF/UC Hastings Consortium, professor, UC Hastings
    Part 3 - Andrew Bindman, MD, professor of medicine, health policy, epidemiology and biostatistics, UCSF
    Part 4 - Josh Adler, MD, chief medical officer, UCSF Medical Center and UCSF Benioff Children's Hospital
    Part 5 - Q&A with Audience

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    Health Reform in Aftermath of Supreme Court Ruling PART 1

    by UCSFPublicAffairs 63 views

    UCSF and UC Hastings experts convened to discuss the impact of the U.S. Supreme Court ruling on the Patient Protection and Affordable Care Act, President Obama's landmark domestic policy.

    The Supreme Court's decision has wide-reaching consequences for health care in America. "What Now? Health Reform in the Aftermath of the Supreme Court Decision," features experts who discuss the legal significance of the decision and the practical implications for health care.

    The forum is sponsored by the UCSF Philip R. Lee Institute for Health Policy Studies, one of the nation's premier centers for health policy and health services research, in conjunction with UC Hastings and the UCSF-UC Hastings Consortium on Law, Science, and Health Policy.

    Part 1 - David Faigman, JD, director UCSF/UC Hastings Consortium, John F. Digardi Distinguished Professor of Law, UC Hastings
    Part 2 - Jaime King, JD, PhD, associate directors, UCSF/UC Hastings Consortium, professor, UC Hastings
    Part 3 - Andrew Bindman, MD, professor of medicine, health policy, epidemiology and biostatistics, UCSF
    Part 4 - Josh Adler, MD, chief medical officer, UCSF Medical Center and UCSF Benioff Children's Hospital
    Part 5 - Q&A with Audience

  74. 76

    PTSD May Pose Greater Risk to Women in the Military — and in Civilian Life

    by UCSFPublicAffairs 682 views

    http://www.ucsf.edu/news/2012/08/12557/women-may-be-increase­d-health-risk-due-ptsd
    Stress and trauma can be a big part of a warrior's life, including women warriors. Today, one in seven in active U.S. military service is a woman. New research by Aoife O'Donovan, PhD, a UCSF scientist from the San Francisco VA Medical Center, suggests that women may be more vulnerable to post-traumatic stress disorder (PTSD). Women with PTSD might be more likely than men with PTSD to be biologically affected in ways that may hasten aging, and that increase risk for diseases of aging.

  75. 77

    Three Snakes That Shook the World

    by UCSFPublicAffairs 8,234 views

    http://www.ucsf.edu/news/2012/08/12545/mysterious-snake-dise­ase-decoded
    A novel virus of a type that was thought never to infect snakes at all has been identified as the possible cause of the common but mysterious "inclusion body disease", which kills a significant number of pet snakes all over the world, thanks to research led by scientists at the University of California, San Francisco (UCSF)—and three snakes named Juliet, Balthazar and Larry.

    UCSF's Joe DeRisi described this work, which paves the way toward developing diagnostics and treatments and may make it possible to eradicate the disease from snake collections worldwide. Long the bane of zoo masters and exotic pet owners, the deadly and devastating disease spreads among boas and pythons in captivity, causing micro clumps of clustered proteins to form inside the snake, leading to bacterial infections, neurological problems, anorexia and withering, leading to death.

    Joe DeRisi, PhD, is a Howard Hughes Medical Institute investigator (HHMI) and vice chair of the Department of Biochemistry and Biophysics at UCSF.

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    How HIV Unfolded in Uganda

    by UCSFPublicAffairs 32 views

    Moses Kamya, MB, ChB, MMed, MPH, PhD, a professor and chair of the department of medicine at Makerere University in Kampala Uganda, talks about AIDS and its effect in Uganda.

    Here he talks about how the harsh reality in which the epidemic unfolded.

    "The moment you knew that you had HIV, you would have to sign a will," he said, "because you knew that death was coming."

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    When AIDS Came to Uganda

    by UCSFPublicAffairs 84 views

    Moses Kamya, MB, ChB, MMed, MPH, PhD, a professor and chair of the department of medicine at Makerere University in Kampala Uganda talks about AIDS and its effect in Uganda.

    Here he talks about the first case of AIDS he saw in Uganda, a friend and medical student in his class came down with what was called "slim disease."

    "My classmate came down with a strange illness, which he told us was killing people in his village," he said.

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    Mark Dybul on PEPFAR

    by UCSFPublicAffairs 322 views

    Ambassador Mark Dybul, who co-directs the Global Health Law Program at Georgetown University Law Center's O'Neill Institute for National and Global Health Law, where he is also a Distinguished Scholar. Here he talks about U.S. President's Emergency Plan for AIDS Relief (PEPFAR).

    Dybul was formerly the PEPFAR administrator as the United States Global AIDS Coordinator from 2006 to the end of the George W. Bush administration. Here he talks about the keys to PEPFAR's success

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    Moses Kamya on PEPFAR

    by UCSFPublicAffairs 55 views

    In the case of HIV/AIDS we know treatment and prevention work and we know that one of the most successful examples of this is the U.S. President's Emergency Plan for AIDS Relief (PEPFAR)

    Here Moses Kamya, MB, ChB, MMed, MPH, PhD, a professor and chair of the department of medicine at Makerere University in Kampala Uganda talks about PEPFAR and its effect in Uganda.

    "PEPFAR is one of the best things that has happened to us," he said. "Looking at people who are desperate, people who are destined to die -- I think the American people were very generous to offer support."

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    The Need for AIDS Activism Globally

    by UCSFPublicAffairs 26 views

    More on activism from retired UCSF professor Art Ammann. Here he discusses the need for global activism to confront HIV/AIDS worldwide.

    "Why is a person going to change their behavior -- why is a government going to change its behavior? They're not going to rudy the literature and go over things and say, "We're going to do this,'" Ammann said. "It really has to come from the people."

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    How do TB drugs interact with HIV drugs?

    by UCSFPublicAffairs 435 views

    In January, 2012, the U.S. Food and Drug Administration (FDA) issued new guidelines on dosing of an HIV medication used to treat people infected with both HIV and tuberculosis (TB) because of a potential interaction between two of the main drugs used to treat each disease.

    The drug rifampin, used for treating TB, can lower levels of the HIV medicine efavirenz, so the FDA recommended that patients who weigh more than 50 kg (110 pounds) and who are taking both medications should get 30 percent larger doses of efavirenz (an increase from 600 mg to 800 mg).

    Now, a new analysis by conducted by researchers with the Adult AIDS Clinical Trials Group (ACTG) at the University of California, San Francisco (UCSF) and the San Francisco General Hospital and Trauma Center (SFGH) suggests this recommended dose adjustment may not be necessary, particularly in non-Caucasian populations.

    As described in a talk at the XIX International AIDS Conference in Washington, D.C. on Monday, July 23, 2012, the new FDA guidelines were based on several small studies in European TB patients and one in healthy volunteers, indicating a decrease in efavirenz levels with rifampin. The guidelines were also informed by a mathematical model, which showed that increasing efavirenz to 800 mg when given with rifampin would increase levels to those seen on the regular dose of 600 mg.

    These data may not apply to patients in African and Asian populations because of genetic differences that lead to higher efavirenz levels—or even in the United States, where more than half the people with TB and HIV co-infections are African American or Asian American.

    Annie Luetkemeyer is an Assistant Clinical Professor of Medicine at the University of California, San Francisco (UCSF) and Medical Director of the UCSF Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH). She is also an attending physician in SFGH's Positive Health Practice, an investigator in the Adult AIDS Clinical Trials Group (ACTG), and the director of the San Francisco General Hospital HIV Clinical Trials Group (HCTG).

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    How does early HIV therapy improve economic productivity?

    by UCSFPublicAffairs 131 views

    UCSF's Elvin Geng describes a first-of-its-kind clinical study in Uganda that compared socioeconomic outcomes with CD4+ counts—a standard measure of health status for people with HIV—showed that adults with HIV in rural sub-Saharan Africa who receive antiretroviral drugs early in their infection, they may reap benefits in their ability to work and their children's ability to stay in school

    The study, presented at XIX International AIDS Conference in Washington, D.C. on 7.26.12, found that people infected with HIV who had high CD4+ counts were able to work 30 percent more hours per day and their children had school enrollment rates that were 15 percent higher than the children of people with low CD4+ counts.

    The discovery, by researchers in the Gillings School of Global Public Health at University of North Carolina at Chapel Hill, is the result of one piece of a larger study, called the Sustainable East Africa Research in Community Health (SEARCH) Collaboration, led by doctors at the University of California, San Francisco (UCSF), San Francisco General Hospital and Trauma Center (SFGH) and Makerere University in Kampala, Uganda.

    Elvin Geng, MD, is an assistant professor in the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH)

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    How did pediatrics play a role in the AIDS epidemic?

    by UCSFPublicAffairs 31 views

    Former UCSF professor Art Ammann voices the frustration of a pediatrician trying to call attention to young people with AIDS in the early days of the epidemic -- a cause taken up and championed by the activists.

    "We had to struggle in terms of getting funding for the research in children," Ammann said. "We had to struggle in terms of drug development, but where we got help was from the activist community."

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    Why is confronting stigma important to do globally?

    by UCSFPublicAffairs 66 views

    Michel Sidibé, the Executive Director of UNAIDS and Under Secretary-General of the United Nations and one of the featured speakers at the XIX International AIDS Conference in Washington, D.C., has focused on ending discrimination and stigma as an important issues moving forward for confronting HIV worldwide. When Sidibé came to the San Francisco Bay Area on a "listening tour" a few weeks before the meeting to talk about his plan for 2015, he spoke about this issue.

    "It is our choice," he said. "We can end discrimination. We can really decide to say, 'we don't want any more of those bad laws,' which are homophobic or which will discriminate people for what they are or for who they love."

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    AIDS Virus May Speed Aging, UCSF Researchers Find

    by UCSFPublicAffairs 78 views

    HIV might be triggering chronic, harmful, low-level inflammation that impacts many chronic diseases of aging. Treatment is associated with toxicities that may do damage over time, and some are associated with increased cholesterol, regarded as a risk factor for heart disease. UCSF AIDS researcher Steven Deeks, MD, wants to know if earlier treatment of HIV infection will prevent signs of early aging. To reduce inflammation in HIV patients he advocates healthy lifestyle changes, and he wants to evaluate drugs with anti-inflammatory effects.

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    UCSF Medical Center CEO Looks to the Future

    by UCSFPublicAffairs 1,116 views

    http://www.ucsf.edu/news/2012/07/12439/ucsf-medical-center-c­eo-looks-future
    Mark Laret, chief executive officer of UCSF Medical Center and UCSF Benioff Children's Hospital, shares his perspective on recent medical center successes, and challenges and priorities for the coming year.

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    What will it take to get to zero?

    by UCSFPublicAffairs 41 views

    Michel Sidibé, the Executive Director of UNAIDS and Under Secretary-General of the United Nations, one of the featured speakers at the XIX International AIDS Conference in Washington, D.C. this week, is calling for an end to HIV transmission from mother-to-child, which continues to occur hundreds of thousands of times a year.

    In this video

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    New UCSF app to help runners during medical emergencies will debut at San Francisco Marathon

    by UCSFPublicAffairs 86 views

    A new mobile app created by UCSF orthopaedic doctor Anthony Luke, MD, stores HIPAA-compliant and secure medical and personal information electronically. The goal is to help runners during emergencies and it's on a need-to-know basis to the medical team. It will debut at Sunday's San Francisco Marathon on July 29, 2012.

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    The SEARCH Community Health Campaign

    by UCSFPublicAffairs 51 views

    In this video, UCSF assistant professor Gabriel Chamie describes the first results of a study called the Sustainable East Africa Research in Community Health (SEARCH) Collaboration and how it was designed to deal with multiple diseases -- work presented at the XIX International AIDS Conference in Washington, D.C. and led by doctors at the University of California, San Francisco (UCSF), San Francisco General Hospital and Trauma Center (SFGH) and Makerere University in Kampala, Uganda.

    In the study, some 4,343 people were offered HIV testing, and 189 of them tested positive. Nearly half were new diagnoses — meaning that the other half were tested even though they knew they had the disease — and their CD4+ cell counts, on average, were in the mid-400s — indicating they were in the early stages of disease, before a decline towards AIDS. Often regional health centers in Uganda don't identify new cases until a much more advanced stage of the disease.

    The team also tested people for malaria, tuberculosis, diabetes and hypertension and offered counseling, treatment and prevention methods to address those conditions.

    Gabriel Chamie, MD, MPH, is an assistant professor in the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH)

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    How is technology speeding up the detection of HIV and TB

    by UCSFPublicAffairs 142 views

    A new, sensitive and rapid test for tuberculosis (TB) helped researchers detect the disease in a recent clinical study in Uganda -- work presented today at the XIX International AIDS Conference in Washington, D.C. by UCSF assistant professor Gabriel Chamie.

    TB is the number one killer of people with HIV around the globe, and the old way of testing always relied on culturing the bacteria from the lung of infected people -- a time, consuming process that generally requires centralized laboratories.

    "Typically when we're diagnosing TB, the gold standard is culture, and it takes 6-8 weeks," said Chamie, but the new test allows a result to be obtained within a day. "If we had a positive result we could go out and get them treatment."

    Gabriel Chamie, MD, MPH, is an assistant professor in the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH)

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    Why address HIV and TB at the same time?

    by UCSFPublicAffairs 103 views

    Here UCSF assistant professor Gabriel Chamie discusses why it makes sense to address TB and HIV at the same time in many parts of the world. "You can really dramatically reduce the incidence of active tuberculosis," said Chamie, "which in turn can reduce transmission from person to person."

    Chamie spoke today about a study from the "Sustainable East Africa Research in Community Health (SEARCH) Collaboration," which is led by doctors at the University of California, San Francisco (UCSF), San Francisco General Hospital and Trauma Center (SFGH) and Makerere University in Kampala, Uganda.

    Gabriel Chamie, MD, MPH, is an assistant professor in the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH)

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    What is the cascade of care for people with HIV?

    by UCSFPublicAffairs 76 views

    Diane Havlir discusses the cascade of care faced by people with HIV -- all the reasons why people fall out of care and the possible ways of addressing that issue.

    Diane Havlir, MD, is the chief of the UCSF Division of AIDS at San Francisco General Hospital and Trauma Center (SFGH) and the co-chair of AIDS 2012, the XIX International AIDS Conference.

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    Why is TB the leading cause of death worldwide for people with HIV?

    by UCSFPublicAffairs 127 views

    Many of the talks at the XIX International AIDS Conference in Washington, D.C. are focused on the epidemic worldwide, including problems with HIV and tuberculosis (TB), the number one killer of people with HIV around the globe.

    In this video, UCSF assistant professor Gabriel Chamie discusses why TB is such a problem, how HIV makes TB worse, how HIV complicates TB diagnoses, and how it contributes to the spread of TB. These are several of the reasons why modern approaches to the global HIV epidemic seek to address both diseases at the same time.

    Gabriel Chamie, MD, MPH, is an assistant professor in the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH)

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    Preview of AIDS 2012

    by UCSFPublicAffairs 63 views

    Diane Havlir, MD, the chief of the UCSF Division of AIDS at San Francisco General Hospital and Trauma Center (SFGH), is the co-chair of AIDS 2012, the XIX International AIDS Conference. Here she gives a preview of the conference:

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    The first pediatric cases of HIV/AIDS

    by UCSFPublicAffairs 98 views

    Former UCSF professor Art Ammann discusses the frustration he faced as he tried to call attention to several patients with AIDS. Ammann was part of a vanguard of doctors at UCSF who began meeting after they started seeing the first cases of AIDS. It's hard to imagine today, but Ammann's discovery and characterization of the first two pediatric cases was ignored and refuted—and not by the denialists. It from within the medical establishment itself, he said, where the resistance came.

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    Who in San Francisco gets treatment for HIV?

    by UCSFPublicAffairs 137 views

    In 2010 San Francisco became the first city to institute a policy of offering treatment to everybody with HIV. Here Diane Jones, RN, a nurse at the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center, talks about how that works in practice.

    "Most people who we offer [antiretroviral therapy] to want it," said Jones, who has worked for 30 years as an HIV/AIDS nurse at Ward 86. "Between 80 and 90 percent of our 3,000-plus patients are on antiretroviral therapy."

    There are still issues to be faced in getting medicine to people who want to take them, she said, including navigating insurance and benefit programs and dealing with stigma.

    Diane Jones, RN is a nurse at the University of California, San Francisco (UCSF) Positive Health Program at San Francisco General Hospital and Trauma Center (SFGH).

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    Pioneering AIDS Researcher Receives Major Accolade from the American Dental Association

    by UCSFPublicAffairs 239 views

    John Greenspan, BDS, PhD, considers himself naturally curious. When he started seeing a rare form of cancer of the lymphatoid system in young San Francisco men during the early 1980s, he was intrigued.

    "It's called Burkitt's lymphoma and I thought this was strange," said Greenspan, a distinguished professor of oral pathology with the UCSF Department of Orofacial Sciences, and the Associate Dean for Global Oral Health with the UCSF School of Dentistry. "We typically saw it in Africa, but in this country, we only used to see it rarely, for example in immunosuppressed patients, such as kidney transplant recipients. So we ended up seeing one of the first AIDS lymphoma patients reported in the world and I really got hooked."

    His tenacity has led to major research breakthroughs in the oral aspects of AIDS and the role of viruses in oral lesions. In recognition of Greenspan's work, the American Dental Association (ADA) this week named him the recipient of its 2012 ADA Gold Medal Award for Excellence in Dental Research, one of the top honors in the field of American dentistry.

    "I've known most of the people who have received this award and several of them are my personal heroes," Greenspan said. "So there is a tremendous sense of pride."

    It is also a source of pride for the UCSF School of Dentistry.
    "The award of this prestigious medal by the ADA to Dr. Greenspan not only recognizes his groundbreaking work but also sets aside UCSF and the UCSF School of Dentistry as an institution where such work is fostered and conducted," said John Featherstone, MSc, PhD, dean of the UCSF School of Dentistry. "It brings honor and prestige to both the recipient and to UCSF."

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    Short Version: Chancellor to Form Board to Help UCSF Fulfill its Public Mission

    by UCSFPublicAffairs 557 views

    http://www.ucsf.edu/news/2012/07/12358/chancellor-appoint-bo­ard-directors-ensure-ucsfs-ability-deliver-its-public
    UCSF will form a dedicated advisory board to help ensure that the University continues to excel as a health sciences innovator and deliver on its critically important public mission, Chancellor Susan Desmond-Hellmann, MD, MPH, told the UC Regents on July 18, 2012.

    The new UCSF board will serve as strategic advisors to the chancellor and, through the chancellor, to UC President Mark Yudof and the Board of Regents, Desmond-Hellmann told the Regents with members of her leadership team at her side at UCSF Mission Bay.

    "Among the 10 campuses, UCSF is uniquely challenged as the only campus solely focused on the health sciences," she told the Regents. "The crisis in health care, diminishing state support, rising student debt, escalating employee benefit costs and downward pressure on research funding have created a 'perfect storm' in the competitive health sciences marketplace which requires urgent action."

    "The working group proposed the appointment of a group of dedicated directors with operational and strategic expertise to guide UCSF through these challenging times," Desmond-Hellmann told the Regents.

    The chancellor said she will return to the Regents in about six months to share the UCSF board's charter, membership and metrics for success.

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