 Well, good morning. Okay, thank you. I'm going to keep my comments very brief because you'll hear from me a few times today. It's quite a difficult task stepping back in for Bill Chin after these two years that he ran it. And I must confess, I thought after having served some time on this committee that I'd be able to graciously retire, but Karun never lets anybody get away that easily, so hence back here. It's great to see so many friends, ex-colleagues. There's a few former bosses in the audience. Thank you for coming. I think this is a terrific meeting. And it's really been incredible to watch the meeting grow and actually thrive now. We're well oversubscribed. Believe it or not, we turned away over 100 people to this meeting that wanted to come. So you are the chosen few that are here. Another thing that strikes me about the meeting, although we label it US India, and rightly so, and a lot of the work that we'll do today is about that, as Karun often says, diseases know no boundaries. You know, this is going to make a global impact to things that we work on today and decide on today. So again, thank you for your participation. As I say, you'll hear from me a few times throughout the day. Now I would like to introduce Dr Elias Serhouni, who's going to give introductory speech. I've had the pleasure of working with Elias for many years now. He was former head of NIH and now global head of research and development at Sinofei. Elias.