 So on behalf of Dr. Mujun Sun, I would like to sincerely thank the Brain Foundation and their donors. And Dr. Sun would also like to thank her co-investigators, Associate Professor Sandy Schultz, Associate Professor Chris Tonkin, and Professor Christopher Sobi. Traumatic brain injury and a stroke are common brain injuries that affect millions of people worldwide, and both lack effective treatments to improve long-term outcomes. The difficulty in developing effective treatments for brain injuries is in large part due to their heterogeneous nature, as there are factors that can modify how the brain responds to injury. For example, toxoplasma gondi is a parasite that infects about one third of the global population. In other words, many people who suffer a brain injury will be infected by toxoplasma gondi at the time of injury. This parasite permanently resides in the brain tissue of infected mammals and can trigger inflammation. Inflammation is also common after brain injury and contributes to brain damage. Despite the high incidence of toxoplasma gondi and brain injury, as well as clear pathological overlap, no study has investigated how this parasite might alter brain injury outcomes. This project will therefore evaluate the possibility that the presence of toxoplasma gondi infection modifies TBI and a stroke outcomes in rats. If toxoplasma gondi infection does change the brain response to injury, this will have important implications for developing optimal treatment strategies in brain injury patients. Thanks again for the support.