 Plants are a valuable source of medicinal drugs with many secondary metabolites being used in various countries as drugs, flavorings, pigments, pesticides and food additives. The commercial importance of these substances has led to an increased interest in secondary metabolism and the use of tissue culture technology for altering production and multiplication of bioactive plant metabolites. In vitro production of secondary metabolites from plant cell suspension cultures is a key step in their commercial production with bioreactors being used for large scale production. The review focuses on the therapeutic applications and recent advancements in the production of important plant pharmaceuticals. This article was authored by MD Safaraj Hussain, Shiba Fareed, Saba Ansari and others.