 The M Health Research Core was created prior to the COVID-19 pandemic to address the need for a centralized resource to support investigator-initiated M Health Research at our institution. During the pandemic, the Core provided essential services such as seminars on trends in M Health Research, case consultations, liaisons with regulatory compliance groups, and online navigation tools for implementing M Health methods and building partnerships with technology vendors. The Core also assisted investigators in quickly transitioning their studies from traditional to remote research methodologies. This article was offered by Katie E. Kenoy, Eric J. Lenz, and Jinje E. Nicole.