 This method simplifies the calculation of the quantitative scale used in CHIP-SEC experiments, reduces the amount of time required to perform the experiment, and generates tracks which can be used to analyze the data. Additionally, we have shown that the data generated by PSYQ-CHIP can be used to generate insights into the underlying biology of the experiment. This article was authored by Bradley M. Dixon, Rihanna Cooper, Robert M. Vaughan, and others.