 Type II diabetes, T2DM, Alzheimer's disease, AD, and insulin resistance are all age-related conditions which have been linked by recent research. It has been found that insulin resistance and impaired insulin signaling may contribute to the progression of these diseases. Additionally, it has been discovered that Alzheimer's disease, AD, shares similarities with type II diabetes, T2DM. Both diseases are characterized by reduced insulin secretion and or action, leading to altered glucose and lipid metabolism and elevated levels of certain compounds in the blood. These findings suggest that there may be a shared underlying mechanism for the development and progression of both diseases. This article was authored by Giuseppe Verdile, Kevin N. Keen, Vinicius F. Cruzat, and others.