 The Colombian Ministry of Health and Social Protection issued Resolution No. 777 on June 2, 2021, which set forth guidelines for resuming restricted economic and social activities following the third wave of COVID-19. This resolution also introduced the Municipal Epidemiological Resilience Index, IREM, a tool designed to help local governments assess their readiness to resume economic activity. However, the lack of a clear definition of epidemiological resilience and the absence of a scientific basis for the index's construction and validation raised questions about its feasibility. This article was authored by Javier Eslavashmalback, Alexander Resturpoanel, Carol Garnizo-Hirino, and others.