 Abstract surface-enhanced Raman scattering, SCRS, is a powerful analytical tool used for detecting and identifying molecules without the need for labels or markers. Flexible SCRS is a new technology that uses flexible substrates instead of traditional rigid substrates, making it more cost-effective and easier to use. This technology has been applied to portable Raman spectrometers, allowing for point-of-care diagnostics and widespread adoption in homes and global markets. This article was authored by Kachin Su, Rui Zhou, Kuniharu Takei, and others.