 This study investigates the effects of a cybererextract on red blood cell, RBC, deformability, which is the ability of cells to modulate their shape to ensure transit through narrow capillaries of the microcirculation. It was found that a cybererextract restored the increase in band 3-tyrosine phosphorylation and SyK kinase levels caused by exposure to 100 mmD galactose, suggesting that it may be able to reduce the oxidative stress induced by galactose. Additionally, a cybererextract partially restored alterations in the distribution of Spectrin, Enkyrin, and Protein 4.1 indicating that it may help restore normal RBC structure. Finally, a cybererextract significantly decreased membrane RBC deformability associated with galactose, suggesting that it could potentially be used as a natural antioxidant for the treatment and or prevention of oxidative stress-related diseases. This article was authored by Sarah Spinelli, Elisabeth Estrafeis, Lucrezia Gambardella, and others. We are article.tv, links in the description below.