 National Center for Advancing Translational Sciences defined translation as the process of turning observations into interventions that are adopted, sustained, and improve health. Dissemination and Implementation, D&I, Sciences are informed by an understanding of the critical role of people and systems in disseminating, adopting, and sustaining innovations within real-world settings. This article was authored by Tara G Mehta, Jane Mahoney, Aaron L. Lepping, and others.