 The study evaluates the effects of wedololactome, WDL, on melanoma, finding that WDL-inhibited cell proliferation, migration, and invasion induced pro-apoptotic protein Bax expression but inhibited anti-apoptotic protein Bcl2 expression, regulated cell cycle proteins through AKT and AMPK signaling, and inhibited melanoma in xenograft-newed mice. This article was authored by Wei Guangpeng and Li Zhong.