 The study did not find any associations between the polymorphisms of P2RY12, RS2046934, ITGA2, RS1126643, ITGB3, RS5918, GP1BA, RS6065, CYP2C19, RS4244285. Genes and the development of resistance to antiplatelet drugs in patients with coronary heart disease, CHD, undergoing coronary artery bypass grafting, CABC. However, carriers of the C. allele of the RS5918 polymorphism of the ITGB3 gene had a higher rate of A.A. induced platelet aggregation than those with the T. allele. This article was authored by K.S. Semishenko, T.S. Mongush, A.A. Kosanova, and others.