 When biological samples are exposed to electrons in cryo-electron microcopy, cryo-EM, proteins exhibit a rapid burst phase of beam induced motion that cannot be corrected with software. This lowers the quality of the initial frames which are the least damaged by the electrons. They are commonly excluded or down-weighted during data processing. This article was authored by Chun-Ling Wu, Regang Xia, Deng Jiezhu, and others.