 Hi, my name is Dhanesh Tafti. I'm a professor in the mechanical engineering department at Virginia Tech, along with my co-author, Hameed Hosanzadegan. This particular paper, which has been published in the Journal of Biotechnology and Bioengineering, reviews the state of the art in computational modeling of thrombus formation and growth and related phenomena such as platelet margenation, activation, adhesion, and embolization. Additionally, we also review the effect of shear stress on these phenomena. In this review paper, we have addressed issues that researchers come across by modeling thrombosis or thrombosis-related processes such as platelet margenation, platelet activation, or embolization. The parameter values are constant in the models that are used or boundary conditions or the applicability of these modeling techniques. We have specifically reviewed computational methods used for modeling platelet activation, including chemical and shear induced activation, platelet adhesion and aggregation, platelet margenation, embolism, which is very crucial in heart attacks, device-induced thrombosis, devices such as left ventricle assist devices or prosthetic heart valves, and thrombus growth in stenose vessels that are very common in both arterial and venous flows. Also, we have introduced the most common blood viscosity models and developed formulas for the effective mass diffusivity of different blood components. The field of numerical modeling of thrombosis is moving in the direction of developing multi-scale modelings that include events happening on the scale of platelets as well as phenomena at macroscale. Also, what seems to be missing in the literature is a lack of more predictive models that can replicate the experimental observations without the need for calibration under specific conditions. Please take a look at our paper entitled Modeling Thrombosis Formation and Growth and contact Dr. Tafti if you have any questions.