 Activin is a protein that plays a role in the development of certain cancers. It has been found to be present at higher levels in tumours compared to healthy tissue, suggesting it may play a role in tumour growth. In this study, researchers investigated how Activin affects the development of skin tumours in mice. They found that Activin increases the number of macrophages in the skin, which leads to the development of tumours. Additionally, they discovered that Activin also attracts monocytes cells into the skin, which further contributes to tumour growth. Finally, they identified specific genes that are expressed in macrophages when exposed to Activin, which are similar to those seen in other types of tumours. By targeting these genes, researchers were able to reduce the number of macrophages and thus slow down tumour growth. This article was authored by Maria Anzafarova, Alexandra Picotucra, Michael Kankrama, and others. We are article.tv, links in the description below.