 This research paper examined the effectiveness of adding isonizid preventive therapy, IPT, to antiretroviral treatment, art, packages and improving adherence to art among adolescents living with HIV, ALHEV, in Sub-Saharan Africa. It found that the addition of IPT to art packages did not significantly increase adherence to art among ALHEV. However, it did identify several factors that could be used to improve adherence to art, such as providing psychosocial services and support, enrolling ALHEV into teen clubs and encouraging self-reinforcement techniques. Additionally, the study found that complex art regimens were associated with decreased adherence to art. This article was authored by Jimmy Bavilliera, Hillary Katsabala, Menard Bvam and others.