 This study examined the relationship between trust in different sources and vaccine hesitancy during the Covid-19 pandemic. The authors found that trust in science was negatively correlated with vaccine hesitancy, while trust in social media and its use as a primary source of information were positively associated with it. Among those who had higher levels of trust in social media, there was also a greater prevalence of conspiracy beliefs, which further contributed to vaccine hesitancy. Additionally, the temporary suspension of the AstraZeneca vaccine in March 2021 led to a significant increase in vaccine hesitancy, particularly among those with lower levels of trust in science, those living in rural areas, women, and those experiencing financial distress. These results suggest that trust is a key factor in determining vaccine hesitancy, and that pro-vaccine campaigns should focus on targeting populations with low levels of trust in science or social media.