 The COVID-19 pandemic has caused a significant number of deaths and has been particularly dangerous for immunocompromised patients, such as those who have undergone lung transplants. Despite the declaration of the pandemic's end, it remains a serious threat to these patients, who are more susceptible to severe illness and death than the general population. Immunosuppressed patients should be vaccinated against COVID-19 and strictly adhere to infection control protocols to reduce their risk of contracting the virus. This article was authored by Filippo Antonacci, Matteo Petroncini, Elena Salvatera, and others.