 The study assessed the impact of seven-valent pneumococcal conjugate vaccine, PCV7, and subsequent vaccines on a Titus media or acute a Titus media, OM, incidence in children aged less than or equal to five years living in Skane or Vastragotalan's region in Sweden between 2005 and 2013. The study used linked regional and national databases to conduct time series analyses, adjusted age period cohort, APC, predictive models, survival analysis using a Cox proportional hazards model, and descriptive interrupted time series analyses. The results showed that OM incidence rates declined following the introduction of PI DCV and PCV13, but only reached statistical significance for PI DCV in the adjusted APC models. Both PI DCV and PCV13 decreased the risk of first OM diagnosis. This article was authored by Mark Edmondson Jones, Telly Steban, Marcus Holtberg, and others. We are article.tv, links in the description below.