 The Amazon rainforest is under threat from deforestation, which can lead to a range of negative effects including the extinction of species, increased risk of flooding and drought, and the spread of infectious diseases. In particular, Brazil is home to the majority of the Amazon rainforest and its deforestation is having a significant effect on the country's public health. The review examines how deforestation contributes to the spread of infectious diseases and suggests potential solutions to mitigate this problem. This article was authored by Joel Enrique L. Wenger, Bruna Kulmanlil, Dauria L. Kaminski, and others.