 3ZN-2, MN-2, Fe-2, nanocomplexes with theophyllin were synthesized using ultrasonic sonication method, and their structure was investigated through various spectroscopic techniques. The nanocomplexes had a size of 6 to 22 nanometers and were highly effective in inhibiting bacterial growth against four types of bacteria, with inhibition zones ranging from 98% to 100%. This article was authored by Amad Hussain Ismail, Hassanain Kamal Al-Bermany, Zainab Sabri Abbas, and others.