 Good morning, everyone. I am Dr. Pooja, junior resident in Redu diagnosis department in PJ MS, Rohtak. I am presenting oral paper on Thanatophoric dysplasia. Thanatophoric dysplasia is the most common lethal skeletal dysplasia with estimated incidence is around 1 to 25,000 to 50,000. It is characterized by disproportionately small ribcage, extremely short limb and force of extra skin on the arms and legs. It results from mutation, coding for the fibroblast growth factor 3, located on chromosome number 48. Inheritance is thought to be sporadic. There are two recognized subtypes. Type 1. In type 1, there is marked undevelopment of skeleton, telephonic handle femur more pronounced. And in type 2, the presence of clover leaf skull may be a distinct feature. Limb shortening is milder and bowing is not a feature. We present a case of 26 year old female presenting for routine antinatal ultrasound examination at the gestational age of 18 week. She was the primary crevita with no family history of any congenital abnormality. Investigation's faster antinatal ultrasounds. On antinatal ultrasound, there was shortening of limb, micromilia, femur was shaped like telephone receiver, small conical bell shaped thorax, abdominal circumference, more than thoracic circumference, and reduced liqueur. There was normal head shape. On x-ray, telephone handle shaped femur, plactis fondly means flattening of vertebral bodies and narrowing chest diameter, normal head shape. These are the x-rays in which in the first image, there is telephonic handle shaped femur. In second, there is plactis fondly, the flattening of vertebral bodies, and third, narrow diameter of chest. In the last image, there is normal head shape. This is antinatal ultrasound. I will show the shortening of limbs called micromilia, femur was shaped like telephone receiver, and small conical bell shaped thorax, abdominal circumference is more than thoracic circumference, and there is normal head shape. Conclusion is Thanatophore dysplasia is a congenital sporadic and elitist skeletal dysplasia at birth. Ultrasonography highly indicates that the diagnosis of Thanatophore dysplasia, but the conformation is done by molecular analysis in prenatal period, clinical features at birth, or by autopsy. Most of the fetus die in utero. The cause of death is due to respiratory insufficiency, which may be secondary to narrow chest cavity and hypoblastic lungs, brain stem compression by narrow foramen magnum or combination of birth. Thank you.