 This review highlights the lack of research on vaccine hesitancy among children and adolescents, argues for more studies in this area, discusses special issues to consider when framing health promotion messages for this population, and explores the use of new and existing technologies as delivery mechanisms for vaccine education. The review also emphasizes the potential impact of children's experiences with vaccines on their future attitudes and behaviors towards vaccines, and suggests that interventions aimed at children can create positive attitudes towards vaccines that may influence parental attitudes as well. This article was authored by Alexander Amazinov, Holio Whitman, Jamie Brehort, and others.