 The urbanization process in Asia is still ongoing, which means that aggregate demand will continue to increase in the coming years. However, construction and demolition waste is not yet an alternative material source in Vietnam due to the ongoing urbanization process. Therefore, there is a need for river sand and aggregates alternatives in concrete, such as manufactured sand, M sand, from primary solid rock materials and secondary waste materials. To address this issue, researchers conducted a series of experiments involving concrete lab tests and a life cycle assessment, LCA. The lab tests involve testing various samples of concrete with different ratios of M sand, secondary waste materials, and cement replacements. The LCA study assessed the environmental impact of these samples, including energy consumption, water usage, and air emissions. The results showed that M sand from primary solid rock materials meets the requirements for quality concrete, while secondary waste materials can be used as partial replacements for cement without compromising the quality of the concrete. Additionally, the LCA study revealed that the use of secondary waste materials has a lower environmental impact than using primary materials. Overall, this study provides valuable insight into the potential of secondary waste materials as viable alternatives. This article was authored by Lohang Anh, Florin Konstantin Mihai, Anna Belisova, and others.