 Liver cirrhosis is characterized by extensive fibrosis of the liver, and understanding the underpinning immunological processes is important in designing intervention. Here authors show that mucosal-associated invariant T cells are instrumental to controlling the balance between profibrogenic and restorative macrophages and inhibiting their activation might reverse liver fibrosis. This article was authored by Morgan Mobiah, Pushpa Hegde, Adele Hamatine, and others.