 There are conflicting results on the effectiveness of pharmacologic interventions for suicide prevention in adolescents. Here, the authors show, in a retrospective registry study from Sweden during 2016 to 2020, that regional utilization rates of clozapine, electroconvulsive therapy and lithium in 15 to 19-year-olds were associated with lower excess suicide death rates in male adolescents. This article was authored by Adrienne Desai Bostrom, Peter Anderson, Mathias Raskanderson, and others.