 Clostridium perfringens is a gram-positive anaerobic bacterium that is commonly found in soil and human intestines. It is also present in the environment and is capable of causing a variety of illnesses in both humans and animals. These include gas gangrene, food poisoning, non-footborne diarrhea, and enterocolitis. The bacterium produces several toxins which are responsible for its virulence, including alpha, beta, epsilon, iota, and theta toxin. Additionally, it has the ability to form spores which allow it to survive in harsh conditions. Clostridium perfringens is also resistant to certain antibiotics, making it difficult to treat. This article was authored by Tomash Grenda, Alexandra Charrose, Magdalena Sopala, and others.