 Biomaterials include bioceramics, biometals, biopolymers, and biocomposites. They play important roles in the replacement and regeneration of human tissues. However, dense bioceramics and dense biometals pose the problem of stress shielding due to their high-yens modulus compared to those of bones. Porous biomaterials exhibit the potential of bone ingroth, which depends on porous parameters such as pore size, pore interconnectivity, and porosity. Unfortunately, a highly porous biomaterial results in poor mechanical properties. Gradient porous biomaterials have many advantages over gradient dense biomaterials and uniform or homogeneous porous biomaterials. Internal pore surfaces of gradient porous biomaterials can be modified with organic, inorganic, or biological coatings and the internal pores themselves can be filled with biocompatible and biodegradable materials or living cells. Gradient porous biomaterials are generally more difficult to fabricate than uniform or homogeneous porous biomaterials. With the development of cost-effective processing techniques, gradient porous biomaterials. This article was authored by Shiging Miao and Dan Sun. We are article.tv, links in the description below.