 The study determined the prevalence, positive predictive value, PPV, and odds ratio, OR, for cervical cancer screening based on different HPV genotypes before and after HPV vaccination. The results suggest that HPV screening tests in the post-vaccination era might perform better if restricted to the HPV types included in the non-availant vaccine, while screening for all 14 HPV types may result in suboptimal balance of harms and benefits. This article was authored by Marie Nygold, Bo T. Hansen, Suzanne Cakejare, and others.