 This paper investigated the role of low-noncoding INA, LNC INA, in the necrotosis process in skin cutaneous melanoma, SKCM. It found that certain LNC INAs are associated with necrotosis in SKCM, and that these LNC INAs can be used to develop a risk model for predicting patient outcomes. This model was then validated against clinical data and showed good accuracy and sensitivity. Additionally, the authors identified two distinct clusters of SKCM patients, one of which had a better prognosis than the other. These results suggest that LNC INAs could potentially be used to stratify patients into different risk categories and informed treatment decisions. This article was authored by Niao Zhong, Lushan Yang, Yizhi Wang, and others.