 This study examined the effect of genetic background, sex, diet, and infection on the development of type 2 diabetes, T2D, and obesity in mice. The researchers found that certain genetic backgrounds, diets, and infections can lead to increased risk of developing T2D and obesity. Additionally, they found that the combination of these factors can be used to predict the outcome of the disease. This article was authored by Balam Lone, Nadav Ben-Nan, Ayugnaam, and others.