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Vasodilation - Vasodilatación

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Uploaded on Mar 29, 2008

ENGLISH: Certain substances (vasodilators; e.g. acetylcholine & prostaglandins) are released to blood in order to regulate the diameter of blood vessels. They interact with specific receptors on endothelial cells, increasing calcium concentration and eliciting synthesis of nitric oxide (NO) gas. NO travels to the following cell layer (smooth muscle cells), stimulating the synthesis of cyclic GMP. Cyclic GMP initiates a cascade of events that eventually results on muscle relaxation and vasodilation.
ORIGINAL URL: http://cgmp.blauplanet.com/pathmovie....

ESPAÑOL: Ciertas sustancias (vasodilatadores; p.ej. acetilcolina y prostaglandinas) son liberadas al torrente sanguíneo para modular el diámetro de los vasos. Interaccionan con receptores específicos en las células endoteliales, aumentando la concentración de calcio y activando la síntesis del gas óxido nítrico (NO). El NO viaja hasta la siguiente capa de células (musculatura lisa del vaso), estimulando la síntesis de GMP cíclico. El GMP cíclico inicia una serie de eventos que dan lugar finalmente a la relajación del músculo y a la vasodilatación.
VIDEO ORIGINAL EN: http://cgmp.blauplanet.com/pathmovie....

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