 amyloid fibrils are clusters of misfolded proteins that are linked together and form insoluble fibres. These fibres are responsible for a variety of diseases such as Alzheimer's and Kreuzfeldt-Jakob disease. Amyloid fibrils can be detected by a dye called fireflavin tea, that this dye binds strongly to amyloid fibrils and produces a bright fluorescent signal when bound. That can be used to measure the amount of amyloid fibrils present in a sample, allowing researchers to monitor their formation and progression. That also does not affect the rate of amyloid fibril formation, so it can be used to study the effects of other compounds on amyloid fibril formation. This article was authored by Christine Schwepp, Tiffany Ewan Lin, Dennis Charm, and others.