 The study examines global attitudes towards immunizations among 65,819 individuals across 67 countries. It finds that overall sentiment towards vaccinations is positive but there is wide variability between countries and regions. Vaccine safety-related sentiment is particularly negative in the European region, with France and Bosnia and Herzegovina having the highest rates of disagreement that vaccines are safe. The oldest age group and Roman Catholics have positive views on vaccine sentiment, while the western Pacific region reported the highest level of religious incompatibility with vaccines. Countries with high levels of schooling and good access to health services are associated with lower rates of positive sentiment. Regular monitoring of vaccine attitudes can identify populations with declining confidence and acceptance, which should be prioritized for further investigation and appropriate interventions to prevent adverse public health outcomes. This article was authored by Heidi J. Larson, PhD, Alexander de Figurito, MSC, Zhao Xiahong, BSC, and others. We are article.tv, links in the description below.