 This paper outlines the steps taken to develop a new type of smart clothing designed to reduce the risk of developing pressure ulcers in people with limited mobility or who are bedridden. The first phase involved identifying the product and process requirements and specifications. Next, the authors investigated the fiber structure technology, textile, and design. They also looked into the sensor technology with regards to pressure, temperature, humidity, and bioactive properties. In the fourth phase, they adapted their production layout and made modifications to the manufacturing process. Finally, they conducted a clinical trial to evaluate the effectiveness of the smart clothing. This article was authored by Anderson de Silva-Rigo, Guillermo Eustaquillo-Fortado, Raphael A. Bernardz, and others.