 Welcome everybody. My name is Mark Williams. I'm one of the co-chairs of this meeting along with Rex Chisholm. And so you'll be seeing way more of me than you probably care to, particularly this early in the morning. It's been great to connect with so many friends. I'm always, at meetings like this, I always think of the penultimate scene of Casablanca, where Louis says to his co-workers, alright, round up the usual suspects. So the usual suspects are all seated around the table and we'll be hearing from most of them during the course of the meeting. We're going to try and do a lot probably more than we should in the day and a half that we have together, so we're going to be ruthless about staying on time. And to that end I will be introducing the first of our welcome speakers, which is the Director of the National Human Genome Research Institute, the sponsoring organization, one of the two sponsoring organizations for this meeting. And before I have Dr. Green come up here, I think we all should congratulate Eric on this. This is his official two-year anniversary of ascending to the directorship of the NHGRI. So that's probably worthy of a little applause.