 Stem cell therapy holds great promise for treating various diseases, including cancer and degenerative conditions such as heart disease and diabetes. Recently, the development of induced pluripotent stem cells, IPSCs, has greatly advanced the field of stem cell research, allowing scientists to create new stem cells from adult cells. While this technology offers great potential, it also carries certain risks, such as the possibility of tumors forming due to the uncontrolled growth of the stem cells. Additionally, the risk of transmitting adventitious agents must be taken into consideration when using stem cells derived from donors. Finally, the risk of immunogenicity must be evaluated prior to any clinical application. This article was authored by Hermsen-Harmph, Korma cell SG and Herbert's Kala A.