 The biodegradable high-strength supermolecular polymer-strengthened hydrogel composed of cleavable poly and acryloid II glycine, PACG, and methacrylate gelatin, gelame, PACG gelame, was successfully constructed by photo-initiated polymerization. Introducing hydrogen bond-strengthened PACG contributed to a significant increase in the mechanical strengths of gelatin hydrogel with a high tensile strength up to 1.1 mPa, outstanding compressive strength, up to 12.4 mPa, large Young's modulus, up to 320 kPa, and high compression modulus, up to 837 kPa. In turn, the gelame chemical cross-linking could stabilize the temporary PACG network, showing tunable biodegradability by adjusting ACG slash gelame ratios. Furthermore, a biohybrid gradient scaffold consisting of top layer of PACG gelame hydrogel MN2 plus and bottom layer of PACG gelame hydrogel bio. This article was authored by Fei Gao, Ziang Su, Qingfeilang, and others. We are article.tv, links in the description below.