 The main objective of this study was to explore the quality of life of patients with multiple myeloma in Europe and we want to identify whether the quality of life differ between patients living in different countries and if quality of life differs between the different treatment options. We found that patients with multiple myeloma have a worse quality of life compared to the general public and especially patients with multiple myeloma experience problems related to fatigue, insomnia and pain but also other dimensions of quality of life for example emotional problems, problems with cognitive functioning are also impaired in patients with multiple myeloma. We did find some differences between patients from different nationalities especially patients from the UK and Germany reported a worse quality of life compared to patients from Italy and other nationalities. Our study does not provide sufficient insight in the main reasons for these differences but my suggestion would be to further explore that by for example interviews with patients why for example the social functioning why they have more problems regarding social functioning and that may help clinicians to improve the treatment for multiple myeloma patients or at least discuss the possibility of problems related to social functioning with patients during the visits at the hospital.