 the study demonstrated that endophytic fungal strains can be used to produce selenium nanoparticles, CNPS. The most efficient producer was penicillium verheginii, which produced ruby red-colored CNPS with a zeta potential of minus 32 mV. The CNPS had a diameter of 25 to 75 nanometers and a concentration-dependent antibacterial effect against E. coli, P. originosa, B. subtilis, S. aureus, C. albicans, C. tropicalis, and C. parasilosis. Furthermore, the CNPS exhibited antioxidant and anti-cancer properties, as well as antilaval activity against AED's albapictus. This article was authored by Abdulrahman A. NASA, Ahmed M. Eid, Hossam M. Atta, and others.